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23397 NCAPH

23397

NCAPH

non-SMC condensin I complex subunit H

protein-coding

Homo sapiens

基因描述

Type Description
Definition non-SMC condensin I complex subunit H

研究结论

Date Results Publications
2021-04-13 10:09:00 HPV E7-mediated NCAPH ectopic expression regulates the carcinogenesis of cervical carcinoma via PI3K/AKT/SGK pathway. 33311486
2020-11-28 13:12:00 Overexpression of MYBL2 promotes proliferation and migration of non-small-cell lung cancer via upregulating NCAPH. 32200471
2020-07-18 11:36:00 miR-199a/b-3p was significantly downregulated in metastatic castration-resistant compared with hormone-sensitive prostate cancer tissues. Ectopic expression of miR-199a/b inhibited cancer cell aggressiveness. The gene coding for NCAPH was directly regulated by miR-199a/b-3p. High expression of NCAPH was significantly associated with poor disease-free survival by The Cancer Genome Atlas database analysis. 30818424
2020-07-18 10:46:00 NCAPH knockdown inhibited cell proliferation, induced cell-cycle arrest at G2/M phase, and prevented colony formation, migration and invasion by NSCLC cells. 32487618
2020-02-08 11:31:00 Findings indicate that non-SMC condensing I complex subunit H (NCAPH) could serve as a prognostic biomarker and a potential therapeutic target for patients with hepatocellular carcinoma (HCC). 31523845

名称对应

Type IDs
Synonymous BRRN1, CAP-H, CAPH, MCPH23
Gene
UniProtKB-ID: CND2_HUMAN, B4DRG7_HUMAN
UniprotKB: Q15003, B4DRG7
UniParc: UPI00017A7C05, UPI0000163F72, UPI00017A8837
EMBL: AC021188, BC024211, AK303725, AK299248, D38553
Ensembl: ENSG00000121152
KO: hsa:23397
Nucleutide sequences
EMBL-CDS: BAA07556.1, AAH24211.1, BAG64701.1, BAG61279.1
Ensembl_TRS: ENST00000240423, ENST00000427946
Protein sequencees
Ensembl_PRO: ENSP00000400774, ENSP00000240423
RefSeq: NP_001268641.1, XP_006712451.1, NP_001268639.1, NP_001268640.1, XP_005263965.1, NP_056156.2
Others
UniRef100: UniRef100_Q15003, UniRef100_B4DRG7
UniRef90: UniRef90_Q15003
UniRef50: UniRef50_Q15003
UniGene: Hs.308045
CCDS: CCDS2021.1, CCDS62960.1

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