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23396 PIP5K1C

23396

PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

研究结论

Date Results Publications
2020-11-21 13:33:00 Type I Phosphatidylinositol-4-Phosphate 5-Kinases alpha and gamma Play a Key Role in Targeting HIV-1 Pr55(Gag) to the 32376619
2020-04-25 11:24:00 our observations revealed that high PIPKIgamma expression in tumor cells could induce AKT-mTOR signaling activation. Increased activation of AKT-mTOR increases the phosphorylation levels of leading to CCL2 expression and suppressing cancer immune reaction activation. 31781676
2019-12-14 10:05:00 Our findings reveal a new regulatory role of PIPKIgamma in Warburg effect and provide a key contributor in colorectal cancer metabolism with potential therapeutic potentials. 31105034
2019-11-09 11:06:00 PIP5K1C was significantly associated with Alcohol Use Disorder in the African ancestry group. However, a replication analysis using an independent sample (N = 3,801) found no significant associations after correction for multiple testing. 29667742
2019-07-13 12:24:00 Cdk5-mediated PIPKIgamma90 phosphorylation is essential for cell invasion leading to breast cancer. 30040488

名称对应

Type IDs
Synonymous LCCS3, PIP5K-GAMMA, PIP5K1-gamma, PIP5Kgamma
Gene
UniProtKB-ID: PI51C_HUMAN
UniprotKB: O60331
UniParc: UPI0001AAAED7, UPI0000203040, UPI0001AAAED6, UPI000019C574
EMBL: AC004637, AC093071, FJ965536, AK315912, AC005542, FJ965537, AB011161
Ensembl: ENSG00000186111
KO: hsa:23396
Nucleutide sequences
EMBL-CDS: BAH14283.1, ACS73484.1, AAC32904.1, BAA25515.1, ACS73483.1
Ensembl_TRS: ENST00000589578, ENST00000335312, ENST00000539785, ENST00000537021
Protein sequencees
Ensembl_PRO: ENSP00000444779, ENSP00000466363, ENSP00000335333, ENSP00000445992
RefSeq: XP_016882029.1, NP_036530.1, XP_011526147.1, NP_001182662.1, XP_011526152.1, XP_011526155.1, NP_001287778.1, XP_011526151.1, XP_011526148.1, XP_011526150.1, XP_011526153.1
Others
UniRef100: UniRef100_O60331
UniRef90: UniRef90_O60331
UniRef50: UniRef50_O70161
UniGene: Hs.282177
CCDS: CCDS32872.1, CCDS74257.1, CCDS56074.1

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