| Type | Description |
|---|---|
| Definition | leucyl-tRNA synthetase 2, mitochondrial |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 10:38:00 | This study adds LARS2 and KARS pathogenic variants as gene defects that may underlie deafness, ovarian failure, and leukodystrophy with mitochondrial signature. | 30737337 |
| 2019-06-29 11:34:00 | We report novel associations between methylation at MSI2 and LARS2 and obesity-related traits. These results provide further insight into mechanisms underlying obesity-related traits, which can enable identification of new biomarkers in obesity-related chronic diseases. | 29762635 |
| 2019-01-12 10:43:00 | We concluded that Perrault syndrome patients with LARS2 mutations are at risk for neurologic problems, despite previous notions otherwise. | 29205794 |
| 2018-07-14 10:55:00 | IARS2 knockdown inhibits proliferation, suppresses colony formation, and causes cell cycle arrest in AGS cells. | 29071539 |
| 2017-07-01 10:55:00 | ere we present eight families affected by Perrault syndrome. In five families we identified novel or previously reported variants in HSD17B4, LARS2, CLPP and C10orf2 | 26970254 |
| Type | IDs |
|---|---|
| Synonymous | HLASA, LEURS, PRLTS4, mtLeuRS |
| Gene |
UniProtKB-ID:
SYLM_HUMAN
UniprotKB:
Q15031
UniParc:
UPI0000001297
EMBL:
D21851,
BC025989
Ensembl:
ENSG00000011376
KO:
hsa:23395
|
| Nucleutide sequences |
EMBL-CDS:
BAA04877.2,
AAH25989.1
Ensembl_TRS:
ENST00000642274,
ENST00000650792,
ENST00000645846
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000495093,
ENSP00000498867,
ENSP00000495707
RefSeq:
NP_001355192.1,
NP_056155.1,
XP_011531856.1,
XP_016861531.1
|
| Others |
UniRef100:
UniRef100_Q15031
UniRef90:
UniRef90_Q15031
UniRef50:
UniRef50_Q15031
UniGene:
Hs.526975
CCDS:
CCDS2728.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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