| Type | Description |
|---|---|
| Definition | activity dependent neuroprotector homeobox |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting. | 33086621 |
| 2020-10-24 14:11:00 | Episignatures Stratifying Helsmoortel-Van Der Aa Syndrome Show Modest Correlation with Phenotype. | 32758449 |
| 2020-07-25 10:13:00 | Our observations provide a novel activity of the autism-linked ADNP in the skin that may serve to define the clinical phenotype of patients with ADNP syndrome and provide an attractive therapeutic option for skin alterations in these patients. | 30679581 |
| 2020-05-02 10:41:00 | We identified ADNP as being amplified and overexpressed in poor prognosis HGSOC in silico analyses and demonstrated that ADNP is a novel and essential oncogene in HGSOC which mediates proliferation through dysregulation of cell cycle checkpoints in vitro. | 31767542 |
| 2020-03-21 10:34:00 | Study describes two distinct episignatures caused by mutations within ADNP. The "epi-ADNP-1" episignature included mostly hypomethylated CpGs, and the "epi-ADNP-2" episignature included predominantly hypermethylated ones. Both of them correlated with the locations of the ADNP mutations. Epi-ADNP-1 mutations occupy the N- and C-terminus, and epi-ADNP-2 mutations are centered on the nuclear localization signal. | 31029150 |
| Type | IDs |
|---|---|
| Synonymous | ADNP1, HVDAS, MRD28 |
| Gene |
UniProtKB-ID:
ADNP_HUMAN,
Q6DHZ8_HUMAN
UniprotKB:
Q9H2P0,
Q6DHZ8
UniParc:
UPI00003E27A0,
UPI00000375B9
EMBL:
BC090933,
AL080163,
AB018327,
AL034553,
CH471077,
AF250860,
BC075794
Ensembl:
ENSG00000101126
KO:
hsa:23394
|
| Nucleutide sequences |
EMBL-CDS:
BAA34504.1,
AAH90933.1,
EAW75611.1,
AAG47651.1,
EAW75612.1,
CAB45752.1,
AAH75794.1
Ensembl_TRS:
ENST00000349014,
ENST00000396029,
ENST00000396032,
ENST00000371602,
ENST00000621696
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000483881,
ENSP00000342905,
ENSP00000379349,
ENSP00000379346,
ENSP00000360662
RefSeq:
XP_011527050.1,
NP_001269461.1,
NP_001269460.1,
NP_001334440.1,
NP_056154.1,
NP_852107.1,
XP_016883248.1,
XP_011527049.1,
XP_016883247.1
|
| Others |
UniRef100:
UniRef100_Q9H2P0,
UniRef100_Q6DHZ8
UniRef90:
UniRef90_Q9H2P0
UniRef50:
UniRef50_Q9H2P0
UniGene:
Hs.570355
CCDS:
CCDS13433.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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