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23392 ECPAS

23392

ECPAS

Ecm29 proteasome adaptor and scaffold

protein-coding

Homo sapiens

基因描述

Type Description
Definition Ecm29 proteasome adaptor and scaffold

研究结论

Date Results Publications
2017-10-21 10:54:00 Data suggest that the adapter protein ECM29 is the main proteasome-interacting protein responsible for oxidative stress-induced proteasome disassembly/remodeling; ECM29 appears to intrude on interaction between the 20S core particle and 19S regulatory particle in 26S proteasome, disrupting proteasome structure in response to oxidative stress. 28821611
2017-02-04 12:28:00 Ecm29 is involved in the dissociation process of 26S proteasome, providing clue to analyse the mechanism of proteasomal degradation under various stress condition. 26802743
2014-05-03 10:47:00 The absence of Ecm29 enhanced TLR3 signaling, which was characterized by the increased abundance of the adaptor protein and E3 ubiquitin ligase tumor necrosis factor receptor-associated factor 3 24084648
2010-11-06 10:26:00 Ecm29 serves as an adaptor for coupling 26 S proteasomes to specific cellular compartments. 20682791
2010-06-30 22:05:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614

名称对应

Type IDs
Synonymous ECM29, KIAA0368
Gene
Nucleutide sequences
Protein sequencees
RefSeq: NP_001351858.1, XP_011516724.1, NP_001351860.1, NP_001350685.1, XP_016870046.1, XP_005251910.1, NP_001351859.1
Others
UniGene: Hs.368255

全选

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研究热度

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