| Type | Description |
|---|---|
| Definition | ring finger protein 40 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 12:29:00 | Rnf40 depletion reduces beta-cell H2Bub1 marks and uncovered several target genes, including glucose transporter 2 (Glut2), MAF BZIP transcription factor A (MafA), and uncoupling protein 2 (Ucp2). RNF40 regulates transcription through imparting monoubiquitin marks on histone H2B (H2Bub1), a precursor to histone H3 lysine 4 trimethylation (H3K4me3). | 31186351 |
| 2019-11-09 11:25:00 | Results suggest that RNF20, RNF40, and H2Bub may represent a novel pathway for DSB sensing and repair. | 30692271 |
| 2019-08-24 12:49:00 | Our findings suggest that RNF40 plays a central role in the maintenance of tumorigenic features and inflammatory signaling by promoting nuclear NF-kappaB activity. | 30321325 |
| 2017-07-08 10:56:00 | Our results support a model in which the direct function of RNF40-mediated H2B monoubiquitination increases transcriptional elongation by promoting the spreading of H3K4me3 into the 5' transcribed region of a select subgroup of genes. | 28209164 |
| 2012-06-02 11:34:00 | We show that Bre1 (human BRE1A/B (RNF20/40) and mouse Bre1a/b (Rnf20/40)) acts as an important suppressor of chromosomal instability | 22354749 |
| Type | IDs |
|---|---|
| Synonymous | AI848422, BRE1-B, mKIAA0661 |
| Gene |
UniProtKB-ID:
BRE1B_MOUSE
UniprotKB:
Q3U319
UniParc:
UPI00000EB711
EMBL:
AK089805,
AK171462,
AK129184,
AK154982,
AK042654,
BC038348
Ensembl:
ENSMUSG00000030816
KO:
mmu:233900
|
| Nucleutide sequences |
EMBL-CDS:
BAC31322.1,
BAE42468.1,
BAE32971.1,
BAC40966.1,
AAH38348.1,
BAC97994.1
Ensembl_TRS:
ENSMUST00000205694
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000146310
RefSeq:
NP_001347812.1,
NP_758485.2,
XP_006507812.1,
XP_006507813.1
|
| Others |
UniRef100:
UniRef100_Q3U319
UniRef90:
UniRef90_O75150
UniRef50:
UniRef50_O75150
UniGene:
Mm.41122
CCDS:
CCDS21871.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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