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23390 ZDHHC17

23390

ZDHHC17

zinc finger DHHC-type containing 17

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger DHHC-type containing 17

研究结论

Date Results Publications
2021-04-13 10:10:00 Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression. 31938047
2018-03-17 10:25:00 Data reveal the structural basis of interaction between DHHC17, and SNAP25b, a canonical substrate. These results show the role of critical residues for substrate binding and palmitate transfer and the involvement of the same residues in binding Huntingtin, another important substrate of DHHC17. 28757145
2017-10-28 11:26:00 The large number of zDABM sequences within the human proteome suggests that zDHHC17 may be an interaction hub regulating many cellular processes. 28882895
2017-03-04 11:12:00 CPj0783 might cause abnormal vesicle-mediated transport by interacting with HIP14. 27611675
2016-01-02 12:06:00 This suggests that altered HIP14-HTT and HIP14L-HTT interactions in the presence of the HD mutation reduces palmitoylation and promotes mislocalization of HTT and other HIP14/HIP14L substrates 25849918

名称对应

Type IDs
Synonymous DHHC-17, HIP14, HIP3, HSPC294, HYPH
Gene
UniProtKB-ID: ZDH17_HUMAN
UniprotKB: Q8IUH5
UniParc: UPI00003519D5, UPI0000051F55, UPI00003519D6
EMBL: AK299089, AB097013, AB024494, AF161412, AF049612, BC030990, AB097035, AB023163, BC050324
Ensembl: ENSG00000186908
KO: hsa:23390
Nucleutide sequences
EMBL-CDS: BAC22089.1, AAH30990.1, BAA76790.1, BAG61151.1, BAC77366.1, BAC77388.1, AAC26848.1, AAH50324.1, AAF28972.1
Gene_ORFName: HSPC294
Ensembl_TRS: ENST00000426126
Protein sequencees
Ensembl_PRO: ENSP00000403397
RefSeq: NP_001346555.1, NP_056151.2
Others
UniRef100: UniRef100_Q8IUH5
UniRef90: UniRef90_Q8IUH5
UniRef50: UniRef50_Q8IUH5
UniGene: Hs.4014
CCDS: CCDS44946.1

全选

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