| Type | Description |
|---|---|
| Definition | MAU2 sister chromatid cohesion factor |
| Date | Results | Publications |
|---|---|---|
| 2019-06-08 11:08:00 | Here, the authors show that, in human cells, cohesin loading onto chromosomes during early S phase requires the replicative helicase MCM2-7 and the kinase DDK. Cohesin and its loader SCC2/4 (NIPBL/MAU2 in humans) associate with DDK and phosphorylated MCM2-7. | 29611806 |
| 2012-06-16 10:42:00 | specific novel mutations at the N-terminus of the MAU2-interacting domain of NIBPL result in markedly reduced MAU2 binding. | 21934712 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| 2010-01-21 00:00:00 | Human MAU-2 family member has weak similarity to yeast Scc4 and is associated with Scc2, bound to chromatin from telophase until prophase, and required for association of cohesin with chromatin during interphase | 16682347 |
| Type | IDs |
|---|---|
| Synonymous | KIAA0892, MAU2L, SCC4, mau-2 |
| Gene |
UniProtKB-ID:
SCC4_HUMAN
UniprotKB:
Q9Y6X3
UniParc:
UPI00000238DA,
UPI00001C200D,
UPI00001C0C4F
EMBL:
AL110250,
AC022543,
AB020699,
BC010222,
AK126227,
BC063863
Ensembl:
ENSG00000129933
KO:
hsa:23383
|
| Nucleutide sequences |
EMBL-CDS:
BAC86497.1,
BAA74915.1,
CAB53698.1,
AAH10222.4
Ensembl_TRS:
ENST00000262815
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262815
RefSeq:
NP_056144.3,
XP_005259895.3,
XP_005259894.2,
XP_016882028.1,
XP_011526146.1,
XP_006722774.2
|
| Others |
UniRef100:
UniRef100_Q9Y6X3
UniRef90:
UniRef90_Q9Y6X3
UniRef50:
UniRef50_Q9Y6X3
UniGene:
Hs.654939,
Hs.744479
CCDS:
CCDS32969.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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