| Type | Description |
|---|---|
| Definition | SMG5 nonsense mediated mRNA decay factor |
| Date | Results | Publications |
|---|---|---|
| 2018-07-07 12:11:00 | The authors found no evidence for the existence of a physical or functional interaction between SMG5 and PNRC2. | 29348139 |
| 2017-09-16 12:41:00 | This study highlights that miR-433 represses nonsense mediated mRNA decay. The miR-433 targets 3'-UTR of SMG5 and represses the expression of SMG5, whereas nonsense-mediated mRNA decay activity is decreased when SMG5 is decreased. | 27473591 |
| 2015-06-20 10:09:00 | Depletion of nonsense-mediated mRNA decay pathway components Upf1, Smg5, and Smg7 led to increased levels of viral proteins and and virus release. | 25211080 |
| 2014-11-08 10:52:00 | The study demonstrates that SMG5-SMG7 and SMG6 exhibit different and non-overlapping modes of UPF1 recognition, thus pointing at distinguished roles in integrating the complex nonsense-mediated mRNA decay interaction network. | 25013172 |
| 2010-01-21 00:00:00 | Data show that phosphorylated hUPF1, the human ortholog of UPF1/SMG-2, forms a complex with human orthologs of the Caenorhabditis elegans proteins SMG-5 and SMG-7. | 14636577 |
| Type | IDs |
|---|---|
| Synonymous | EST1B, LPTS-RP1, LPTSRP1, SMG-5 |
| Gene |
UniProtKB-ID:
SMG5_HUMAN
UniprotKB:
Q9UPR3
UniParc:
UPI0000050C24
EMBL:
BC038296,
CH471121,
AL137738,
AL589685,
BC007453,
AY336728,
AY168922,
AB029012,
AB085691,
AL135927
Ensembl:
ENSG00000198952
KO:
hsa:23381
|
| Nucleutide sequences |
EMBL-CDS:
CAH56374.1,
AAH07453.2,
EAW52973.1,
AAQ84301.1,
AAH38296.1,
BAC53623.1,
EAW52974.1,
BAA83041.2,
AAO17582.1
Ensembl_TRS:
ENST00000361813
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355261
RefSeq:
NP_001310546.1,
NP_001310544.1,
NP_001310545.1,
NP_056142.2,
NP_001310543.1
|
| Others |
UniRef100:
UniRef100_Q9UPR3
UniRef90:
UniRef90_Q9UPR3
UniRef50:
UniRef50_Q9UPR3
UniGene:
Hs.516837
CCDS:
CCDS1137.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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