| Type | Description |
|---|---|
| Definition | SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:02:00 | SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. | 31565865 |
| 2017-12-16 11:46:00 | smg-1 mutations confer strong hyper-sensitivity to IR. SMG-1 does not appear to act in any of the three major pathways known to mend DNA DSBs. | 28634159 |
| 2011-01-01 11:14:00 | The CK2 phospho-dependent interaction between TEL2 and the R2TP complex affects phosphatidylinositol 3-kinase-related kinase functions and is essential for mTOR and SMG1 stability in vivo. | 20864032 |
| 2010-09-06 11:31:00 | Results demonstrate a critical role for Smg1 in early mouse development and link the loss of this NMD factor to major and widespread changes in the mammalian transcriptome. | 20566848 |
| Type | IDs |
|---|---|
| Synonymous | 2610207I05Rik, 5430435M13Rik, C130002K18Rik, mKIAA0421 |
| Gene |
UniProtKB-ID:
SMG1_MOUSE
UniprotKB:
Q8BKX6
UniParc:
UPI00006E225E,
UPI00000EB50B,
UPI0000511C29
EMBL:
AK047829,
AK220328,
AC131788,
AK129136,
AC132432,
AK049391,
AK041264,
AK052331
Ensembl:
ENSMUSG00000030655
KO:
mmu:233789
|
| Nucleutide sequences |
EMBL-CDS:
BAD90238.1,
BAC33729.1,
BAC33168.2,
BAC30884.2,
BAC34941.1,
BAC97946.1
Ensembl_TRS:
ENSMUST00000032891
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032891
RefSeq:
XP_006507740.1,
XP_006507741.1,
NP_001026984.1,
XP_030098366.1
|
| Others |
UniRef100:
UniRef100_Q8BKX6
UniRef90:
UniRef90_Q8BKX6
UniRef50:
UniRef50_Q96Q15
UniGene:
Mm.309053
CCDS:
CCDS40102.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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