| Type | Description |
|---|---|
| Definition | INSC spindle orientation adaptor protein |
| Date | Results | Publications |
|---|---|---|
| 2016-08-06 11:08:00 | Excess mINSC drives symmetric cell division, more stem cells and enhanced mammary outgrowth. | 26440891 |
| 2016-07-16 11:28:00 | Data (including data from studies using embryonic stem cell line) suggest that expression of Insc (inscuteable cell cycle protein) is up-regulated by c-Rel in cell differentiation; minimum transcriptional regulatory element (354 bases) was identified. | 26694615 |
| 2014-12-20 10:06:00 | support for the hitherto untested model that Par3-mInsc and Galphai3 act cooperatively to polarize LGN and promote perpendicular divisions | 25016959 |
| 2013-11-02 11:35:00 | Insc controls directional migration via noncanonical G protein signaling, in which Gbetagamma-free Galphai-GDP, a product from Galphai-GTP released after receptor activation, plays a central role. | 23891662 |
| 2011-12-24 10:27:00 | Mouse inscuteable induces apical-basal spindle orientation, which affects the rate of indirect neurogenesis, a process where progenitors give rise to basal progenitors, which in turn divide symmetrically into two differentiating neurons. | 22017987 |
| Type | IDs |
|---|---|
| Synonymous | 3830422K02Rik, C730020D23 |
| Gene |
UniProtKB-ID:
INSC_MOUSE,
G3UW77_MOUSE
UniprotKB:
Q3HNM7,
G3UW77
UniParc:
UPI00001C3E45,
UPI00001F500E,
UPI00000E99EB
EMBL:
DQ205645,
AC102792,
AK050143,
BY236076,
BC139197,
BC139196,
AC110186
Ensembl:
ENSMUSG00000048782
KO:
mmu:233752
|
| Nucleutide sequences |
EMBL-CDS:
ABA54267.1,
BAC34091.1,
AAI39197.1,
AAI39198.1
Ensembl_TRS:
ENSMUST00000169913,
ENSMUST00000117543
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129505,
ENSMUSP00000112682
RefSeq:
XP_006507722.1,
XP_006507727.1,
XP_006507726.1,
XP_036008893.1,
NP_776128.2,
XP_030098360.1,
XP_030098361.1,
XP_006507725.1
|
| Others |
UniRef100:
UniRef100_Q3HNM7
UniRef90:
UniRef90_Q3HNM7
UniRef50:
UniRef50_Q1MX18
UniGene:
Mm.83037
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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