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23373 CRTC1

23373

CRTC1

CREB regulated transcription coactivator 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition CREB regulated transcription coactivator 1

研究结论

Date Results Publications
2020-07-25 11:20:00 Study identified a methylation change during the first month of psychotropic treatment in the CRTC1 gene, which was associated with early weight gain during the same period. This epigenetic modulation was dependent on a genetic variant (rs4808844A>G) in the same genetic region, which plays a considerable regulatory role. 31878957
2020-01-11 10:41:00 These data suggest that increased CRTC1 in maladaptive hypertrophy presents a compensatory mechanism to delay disease progression in part by enhancing Rgs2 gene transcription. 30521840
2019-12-14 12:33:00 Our data support the known role of CRCT1 regulating energy metabolism in brain. Here, we highlight relevance of CRTC1 regulation in blood and adipose tissue 31153815
2019-11-02 11:18:00 Case Reports: identify a novel recurrent gene fusion, CRTC1-SS18, in undifferentiated small round cell sarcoma. 29533464
2019-09-07 12:52:00 Pancreatic mucoepidermoid carcinoma does not have CRTC1/3-MAML2 fusion gene and MAML2 gene rearrangement. 30138216

名称对应

Type IDs
Synonymous MAML2, MECT1, Mam-2, TORC-1, TORC1, WAMTP1
Gene
UniProtKB-ID: CRTC1_HUMAN
UniprotKB: Q6UUV9
UniParc: UPI00001D9A88, UPI0000062269, UPI0000140CBC
EMBL: AC003107, BC017075, AY040323, AC004476, BC023614, BC028050, AK024089, AY040324, AY186998, CH471106, AC006123, AY186997, AY360171, AB014516
Ensembl: ENSG00000105662
KO: hsa:23373
Nucleutide sequences
EMBL-CDS: AAQ98856.1, AAH17075.3, BAA31591.1, AAK93832.1, BAB14822.1, AAH23614.2, AAP12463.1, AAH28050.1, AAC97072.1, EAW84730.1, AAK93833.1, AAP12462.1
Ensembl_TRS: ENST00000321949, ENST00000338797
Protein sequencees
Ensembl_PRO: ENSP00000345001, ENSP00000323332
RefSeq: NP_056136.2, XP_006722773.1, XP_016882026.1, XP_011526144.1, NP_001091952.1, XP_016882025.1, XP_005259892.1, XP_005259893.1, XP_005259891.1, XP_005259890.1, XP_016882027.1, XP_024307202.1
Others
UniRef100: UniRef100_Q6UUV9
UniRef90: UniRef90_Q6UUV9
UniRef50: UniRef50_Q6UUV9
UniGene: Hs.371096
CCDS: CCDS42525.1, CCDS32963.1

全选

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