| Type | Description |
|---|---|
| Definition | Rho/Rac guanine nucleotide exchange factor 18 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 11:49:00 | We suggest that a portion of a 1361-residue isoform of ARHGEF18, which is unlike any other protein domain, has unique functions in control of polarity in activated eosinophils and other leukocytes | 29601110 |
| 2019-02-23 12:14:00 | ARHGEF18 rs3745357 variant is associated with nonidiopathic pulmonary arterial hypertension susceptibility in Chinese population. | 30405854 |
| 2017-05-06 20:26:00 | mutation of ARHGEF18 is a likely cause of inherited retinal dystrophy | 28132693 |
| 2015-12-05 10:26:00 | CRB3A recruits p114RhoGEF and its activator Ehm2 to the cell periphery using both functional motifs of its cytoplasmic tail and increases RhoA activation levels. | 26217016 |
| 2013-08-31 12:36:00 | LKB1 and p114RhoGEF control RhoA activity in bronchial epithelial cells to promote apical junction assembly. | 23648482 |
| Type | IDs |
|---|---|
| Synonymous | P114-RhoGEF, RP78, SA-RhoGEF, p114RhoGEF |
| Gene |
UniProtKB-ID:
ARHGI_HUMAN,
A0A087WZG4_HUMAN
UniprotKB:
Q6ZSZ5,
A0A087WZG4
UniParc:
UPI0003EB0107,
UPI0000D6170D,
UPI0005CFFD47,
UPI00002371B0,
UPI0003EAF298,
UPI000E46658B
EMBL:
AC126754,
AC119396,
AB011093,
BC077721,
KF456490,
AC008878,
KF456488,
AK127045
Ensembl:
ENSG00000104880
KO:
hsa:23370
|
| Nucleutide sequences |
EMBL-CDS:
AAH77721.1,
BAC86801.1,
BAA25447.1
Ensembl_TRS:
ENST00000319670,
ENST00000617428
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000319200,
ENSP00000482647
RefSeq:
XP_011526137.1,
NP_056133.2,
XP_011526142.1,
XP_006722769.1,
XP_011526138.1,
XP_011526141.1,
NP_001354753.1,
NP_001124427.2,
XP_011526143.1,
NP_001354752.1,
XP_011526139.1,
XP_011526140.1,
XP_005272521.1
|
| Others |
UniRef100:
UniRef100_Q6ZSZ5,
UniRef100_A0A087WZG4
UniRef90:
UniRef90_Q6ZSZ5,
UniRef90_A0A087WZG4
UniRef50:
UniRef50_Q6ZSZ5,
UniRef50_Q6ZSZ5-1
UniGene:
Hs.465761,
Hs.736818
CCDS:
CCDS12177.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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