| Type | Description |
|---|---|
| Definition | post-GPI attachment to proteins 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-29 10:11:00 | The authors identified a novel mouse mutant (cleft lip/palate, edema and exencephaly; Clpex) with a hypo-morphic mutation in Post-Glycophosphatidylinositol Attachment to Proteins-2 (Pgap2), a component of the GPI biosynthesis pathway. The Clpex mutation decreases surface GPI expression. They found that the Clpex phenotype is due to apoptosis of neural crest cells (NCCs) and the cranial neuroepithelium. | 31232685 |
| 2010-01-21 00:00:00 | The Frag1 signal pathway, by linking replication stress surveillance with apoptosis induction, plays a central role in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. | 15983387 |
| Type | IDs |
|---|---|
| Synonymous | 1810006G21Rik, C76649, Frag1 |
| Gene |
UniProtKB-ID:
PGAP2_MOUSE,
Q3U6W8_MOUSE,
A0A0R4J1P4_MOUSE
UniprotKB:
Q3TQR0,
Q3U6W8,
A0A0R4J1P4
UniParc:
UPI00001F5C8B,
UPI00005ACC52,
UPI00001F5C87,
UPI000166303F,
UPI000002365F
EMBL:
AK163373,
AK146442,
AC118592,
AK152420,
AK134287,
BC004794,
AK159950,
AK159933,
AK152931,
AC139579
Ensembl:
ENSMUSG00000030990
KO:
mmu:233575
|
| Nucleutide sequences |
EMBL-CDS:
BAE22083.1,
BAE37322.1,
BAE27175.1,
BAE35506.1,
AAH04794.1,
BAE31205.1,
BAE35494.1,
BAE31606.1
Ensembl_TRS:
ENSMUST00000156529,
ENSMUST00000033292,
ENSMUST00000120879,
ENSMUST00000120119
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000114016,
ENSMUSP00000033292,
ENSMUSP00000121521,
ENSMUSP00000113574
RefSeq:
XP_036008889.1,
XP_030098354.1,
NP_001369534.1,
NP_001278287.1,
NP_001361546.1,
NP_001369533.1,
NP_001369525.1,
NP_001369523.1,
NP_001369527.1,
XP_006507707.1,
NP_001369526.1,
XP_006507704.1,
NP_001369532.1,
XP_036008890.1,
XP_030098352.1,
NP_001369536.1,
NP_001369524.1,
NP_001369522.1,
XP_006507712.1,
NP_001369528.1,
XP_006507709.1,
NP_663558.1,
NP_001369530.1,
NP_001369537.1,
XP_036008892.1,
XP_006507711.1,
XP_036008891.1,
NP_001369521.1
|
| Others |
UniRef100:
UniRef100_Q3U6W8,
UniRef100_A0A0R4J1P4,
UniRef100_Q3TQR0
UniRef90:
UniRef90_Q3TQR0,
UniRef90_Q3U6W8
UniRef50:
UniRef50_Q9UHJ9-5,
UniRef50_Q3U6W8
UniGene:
Mm.302013
CCDS:
CCDS40048.1,
CCDS90290.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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