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233571 P2ry6

233571

P2ry6

pyrimidinergic receptor P2Y, G-protein coupled, 6

protein-coding

Mus musculus

基因描述

Type Description
Definition pyrimidinergic receptor P2Y, G-protein coupled, 6

研究结论

Date Results Publications
2021-03-20 13:31:00 P2Y6 Deficiency Enhances Dendritic Cell-Mediated Th1/Th17 Differentiation and Aggravates Experimental Autoimmune Encephalomyelitis. 32554432
2020-06-27 11:09:00 P2Y6 receptor signaling drives an innate macrophage/IL-12/NK cell/IFN-gamma axis that prevents inappropriate allergic type 2 immune responses on respiratory allergen exposure and counteracts the Th2 priming effect of CysLT1R signaling at sensitization 31638598
2020-05-16 10:11:00 P2Y(6) activation on monocytes induces the secretion of the chemokine CXCL8 which may propagate intestinal inflammation. Exacerbated intestinal inflammation in P2Y(6) deficient mice is associated with Th17 activation. 31271845
2018-12-22 11:34:00 Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6. 28539604
2018-10-20 10:46:00 Results demonstrated that P2Y6 signaled through Ca(2+) influx and RhoA/ROCK to reorganize cytoskeleton and promote migration in myoblasts. 28815725

名称对应

Type IDs
Synonymous 2010204J23Rik, P2Y6
Gene
UniProtKB-ID: P2RY6_MOUSE, Q3UQ86_MOUSE
UniprotKB: Q9ERK9, Q3UQ86
UniParc: UPI0000023590
EMBL: BC064095, BC027331, AK142680, AF298899
Ensembl: ENSMUSG00000048779
KO: mmu:233571
Nucleutide sequences
EMBL-CDS: AAH27331.1, AAG24619.1, AAH64095.1, BAE25157.1
Ensembl_TRS: ENSMUST00000060174
Protein sequencees
Ensembl_PRO: ENSMUSP00000055697
RefSeq: XP_011240041.1, XP_036008888.1, NP_898991.1, XP_006507703.1
Others
UniRef100: UniRef100_Q9ERK9
UniRef90: UniRef90_Q63371
UniRef50: UniRef50_Q63371
UniGene: Mm.235193
CCDS: CCDS21507.1

全选

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研究热度

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