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23353 SUN1

23353

SUN1

Sad1 and UNC84 domain containing 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition Sad1 and UNC84 domain containing 1

研究结论

Date Results Publications
2021-01-16 15:59:00 SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells. 31935926
2019-05-04 10:18:00 Progerin overexpression increased levels of SUN1, which couples the nucleus to microtubules through nesprin-2G and dynein, and microtubule association with the nucleus. Reducing microtubule-nuclear connections through SUN1 depletion or dynein inhibition rescued the polarity defects. 30808750
2019-04-20 11:44:00 Results provide evidence that SUN1 is involved in mRNA export and this function is regulated by phosphorylation of serine 113 in the N-terminal domain. 28831067
2019-02-23 11:21:00 Mechanisms of SUN1 Oligomerization in the 29539404
2018-12-22 11:08:00 While Sun1 and Sun2 in HeLa cells are each able to bind KASH-domains, Sun1 is more efficiently incorporated into LINC complexes under normal growth conditions. Furthermore, the balance of Sun1 and Sun2 incorporated into LINC complexes is cell type-specific and is correlated with SRF/Mkl1-dependent gene expression. 29813079

名称对应

Type IDs
Synonymous UNC84A
Gene
UniProtKB-ID: SUN1_HUMAN
UniprotKB: O94901
UniParc: UPI000189260B, UPI00001B2E4D, UPI000013E40E, UPI0001AE7017, UPI0000DAC77C, UPI00001B2E4C, UPI000020E965, UPI00001B2E4B, UPI0000423E9C
EMBL: AF202724, AK302896, BX538211, BC013613, AK309120, AC099731, BC142707, AC073957, AK022469, AK022816, AB018353
Ensembl: ENSG00000164828
KO: hsa:23353
Nucleutide sequences
EMBL-CDS: BAB14046.1, BAA34530.1, AAH13613.1, AAI42708.1, CAD98070.1, BAG64069.1, BAG51119.1, AAF15888.1
Ensembl_TRS: ENST00000403868, ENST00000389574, ENST00000457378, ENST00000425407, ENST00000401592, ENST00000452783
Protein sequencees
Ensembl_PRO: ENSP00000392309, ENSP00000383947, ENSP00000384015, ENSP00000374225, ENSP00000413439, ENSP00000395952
RefSeq: NP_001354609.1, NP_001354619.1, NP_001354587.1, NP_001354628.1, NP_001354602.1, NP_001354611.1, NP_001354596.1, NP_001354570.1, NP_001354629.1, NP_001165415.1, NP_001354606.1, NP_001354569.1, NP_001354627.1, NP_001354618.1, NP_001354597.1, NP_001354614.1, NP_001354634.1, NP_001354584.1, NP_001354625.1, NP_001354564.1, NP_001354595.1, NP_001354594.1, NP_001354598.1, NP_001354593.1, NP_001354612.1, NP_001354580.1, NP_001354621.1, NP_001354562.1, NP_001354574.1, NP_001124437.1, NP_001354575.1, NP_001165416.1, NP_001354577.1, NP_001354626.1, NP_001354591.1, NP_001354604.1, NP_001354616.1, NP_001354563.1, NP_001354632.1, NP_001354572.1, NP_001354600.1, NP_001354605.1, NP_001354599.1, NP_001354623.1, NP_001354571.1, NP_001354610.1, NP_001354633.1, NP_001354578.1, NP_001354635.1, NP_001354582.1, NP_001354566.1, NP_001354576.1, NP_001354589.1, NP_001354613.1, NP_001354603.1, NP_001354617.1, NP_001354637.1, NP_001354630.1, NP_001354565.1, NP_001354608.1, NP_001354622.1, NP_001354615.1, NP_001354601.1, NP_079430.3, NP_001354631.1, NP_001354573.1, NP_001165417.1, NP_001354607.1, NP_001354568.1, NP_001354624.1, NP_001354620.1, NP_001354567.1
Others
UniRef100: UniRef100_O94901
UniRef90: UniRef90_O94901
UniRef50: UniRef50_Q9D666
UniGene: Hs.438072
CCDS: CCDS55080.1, CCDS55079.1, CCDS43533.1, CCDS47525.1, CCDS55078.1

全选

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研究热度

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