| Type | Description |
|---|---|
| Definition | phosphatidylinositol binding clathrin assembly protein |
| Date | Results | Publications |
|---|---|---|
| 2016-05-07 11:27:00 | Confinement within the presynaptic bouton is mediated in part by synaptic vesicle protein association with the clathrin-based endocytic machinery to limit diffusional spread of newly exocytosed SV proteins. | 26399746 |
| 2015-09-26 13:25:00 | the PICALM PIP2 binding domain is necessary for transferrin receptor endocytosis in erythroblasts and absolutely essential for erythroid development from mouse hematopoietic stem/progenitor cells in an erythroid culture system. | 25552701 |
| 2014-05-10 11:04:00 | During leukemogenesis, CALM-AF10 plays critical roles in the cytoplasm. | 24397609 |
| 2013-02-09 11:05:00 | These data reveal that PICALM plays a critical role in iron homeostasis. | 22952941 |
| 2012-08-25 11:31:00 | PICALM, an adaptor protein involved in clathrin-mediated endocytosis, regulates APP internalization and subsequent Abeta generation. PICALM contributes to amyloid plaque load in brain likely via its effect on Abeta metabolism. | 22539346 |
| Type | IDs |
|---|---|
| Synonymous | CALM, CLTH, PAP180, fit-1, fit1, mKIAA4114 |
| Gene |
UniProtKB-ID:
PICAL_MOUSE,
Q570Z8_MOUSE,
Q3TD51_MOUSE
UniprotKB:
Q7M6Y3,
Q570Z8,
Q3TD51
UniParc:
UPI0000006644,
UPI00004FF43E,
UPI000023FF15,
UPI000023FF13,
UPI0000028890,
UPI00001F5AD2,
UPI000023FF14
EMBL:
BC023843,
BK001028,
AK220291,
AY206701,
AK170373,
BC021491,
BC057683,
AK085472,
BC027116,
BC025566,
BC011470,
AK162360
Ensembl:
ENSMUSG00000039361
KO:
mmu:233489
|
| Nucleutide sequences |
EMBL-CDS:
AAO17153.1,
AAH21491.1,
BAE36872.1,
AAH23843.1,
AAH57683.1,
AAH27116.1,
DAA01470.1,
BAC39454.2,
AAH11470.1,
AAH25566.1,
BAD90216.1,
BAE41753.1
Ensembl_TRS:
ENSMUST00000209068,
ENSMUST00000208730,
ENSMUST00000207484,
ENSMUST00000208742,
ENSMUST00000049537,
ENSMUST00000207225
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000146501,
ENSMUSP00000147016,
ENSMUSP00000146659,
ENSMUSP00000051092,
ENSMUSP00000146541,
ENSMUSP00000146386
RefSeq:
XP_006507666.1,
XP_030098335.1,
NP_001347796.1,
XP_006507662.1,
NP_001239450.1,
NP_001239451.1,
XP_030098334.1,
XP_006507658.1,
XP_006507663.1,
XP_006507668.1,
XP_006507665.1,
NP_001239452.1,
XP_006507667.1,
NP_666306.2,
XP_006507659.1,
XP_030098336.1,
NP_001239453.1,
XP_006507660.1,
XP_006507657.1,
XP_006507661.1,
NP_001239449.1
|
| Others |
UniRef100:
UniRef100_Q7M6Y3,
UniRef100_Q7M6Y3-5,
UniRef100_Q3TD51
UniRef90:
UniRef90_O55012-2,
UniRef90_Q13492
UniRef50:
UniRef50_Q13492
UniGene:
Mm.235175,
Mm.393563
CCDS:
CCDS85335.1,
CCDS85334.1,
CCDS85337.1,
CCDS85336.1,
CCDS85338.1,
CCDS52307.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员