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233406 Prc1

233406

Prc1

protein regulator of cytokinesis 1

protein-coding

Mus musculus

基因描述

Type Description
Definition protein regulator of cytokinesis 1

研究结论

Date Results Publications
2020-08-22 15:28:00 Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes. 32461611
2020-04-25 10:50:00 The results suggest that histone H1-dependent chromatin compaction plays a critical role in the stable propagation of H2AK119ub1 by RYBP/YAF2-PRC1 during cell division. 32203418
2019-05-25 12:05:00 Results indicate that Ub-independent mode of repression by PRC1 plays a key role in mammalian development during cell fate restriction. 30562514
2017-12-02 11:40:00 Authors analyzed whether elevated levels of the polycomb repressor complex 1 (PRC1) components Bmi1 and Ring1b and their catalyzed histone modification H2AK119ub in ADMs and tumor cells, are responsible for the mediation of acinar gene silencing. 26716510
2017-11-04 12:42:00 Here, the authors discover that the histone H2AK119 E3 ubiquitin ligase activity of Polycomb repressive complex 1 (PRC1) is defined by the composition of its catalytic subunits and is highly regulated by RYBP/YAF2-dependent stimulation. 27705745

名称对应

Type IDs
Synonymous D7Ertd348e
Gene
UniProtKB-ID: PRC1_MOUSE, G3UY19_MOUSE, G3UW86_MOUSE, G3UWQ7_MOUSE
UniprotKB: Q99K43, G3UY19, G3UW86, G3UWQ7
UniParc: UPI00021CF638, UPI00015DF0B5, UPI000154A93C, UPI000154A93A
EMBL: BC005475, AC136740, AK029140, AC109232
Ensembl: ENSMUSG00000038943
KO: mmu:233406
Nucleutide sequences
EMBL-CDS: BAC26320.1, AAH05475.1
Ensembl_TRS: ENSMUST00000047558, ENSMUST00000173824, ENSMUST00000163812, ENSMUST00000174172
Protein sequencees
Ensembl_PRO: ENSMUSP00000043379, ENSMUSP00000133910, ENSMUSP00000129675, ENSMUSP00000133387
RefSeq: NP_001272926.1, NP_001369317.1, NP_001369315.1, XP_006540918.1, NP_660132.2, NP_001369319.1, NP_001369316.1, NP_001369314.1, NP_001369318.1, NP_001272927.1, NP_001361553.1
Others
UniRef100: UniRef100_G3UWQ7, UniRef100_G3UY19, UniRef100_G3UW86, UniRef100_Q99K43
UniRef90: UniRef90_Q99K43
UniRef50: UniRef50_O43663
UniGene: Mm.227274
CCDS: CCDS71985.1

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