| Type | Description |
|---|---|
| Definition | VPS39 subunit of HOPS complex |
| Date | Results | Publications |
|---|---|---|
| 2015-05-16 11:43:00 | TLP expression contributes to hypertrophic scar formation and contraction. | 25655281 |
| 2013-08-10 11:47:00 | TLP likely acts as a molecular modulator capable of altering the balance of Smad3- and Smad2-dependent signaling through regulation of phosphorylation, thus facilitating collagen synthesis in fibroblasts. | 23418473 |
| 2013-06-15 11:04:00 | Vps39 knockdown impairs late endosome fusion and fusion between late endosomes and lysosomes. | 23167963 |
| 2011-07-16 11:30:00 | Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus | 21454559 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| Type | IDs |
|---|---|
| Synonymous | TLP, VAM6, hVam6p |
| Gene |
UniProtKB-ID:
VPS39_HUMAN,
A0A024R9L9_HUMAN
UniprotKB:
Q96JC1,
A0A024R9L9
UniParc:
UPI000013E629,
UPI0000169BB1
EMBL:
AF334400,
AC036103,
AF280814,
BC015817,
CH471125,
AF281052,
BC068559,
BX537404,
AB018313
Ensembl:
ENSG00000166887
KO:
hsa:23339
|
| Nucleutide sequences |
EMBL-CDS:
AAH15817.2,
AAK72222.1,
CAD97646.1,
AAQ05978.1,
EAW92536.1,
BAA34490.2,
AAH68559.1,
AAK58862.1,
EAW92538.1
Gene_ORFName:
hCG_40427
Ensembl_TRS:
ENST00000348544,
ENST00000318006
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000326534,
ENSP00000335193
RefSeq:
XP_011519706.1,
NP_001288067.1,
XP_016877527.1,
XP_011519705.1,
XP_016877528.1,
XP_016877525.1,
XP_016877526.1,
NP_056104.2
|
| Others |
UniRef100:
UniRef100_A0A024R9L9,
UniRef100_Q96JC1
UniRef90:
UniRef90_Q96JC1,
UniRef90_G1KQX9
UniRef50:
UniRef50_Q96JC1
UniGene:
Hs.88025
CCDS:
CCDS10083.1,
CCDS73710.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32838362 |
Med (N Y) Jingjiao Li , Mingquan Guo , Xiaoxu Tian , Xin Wang , Xing Yang , Ping Wu , Chengrong Liu , Zixuan Xiao , Yafei Qu , Yue Yin , Chunxia Wang , Yucai Zhang , Zhaoqin Zhu , Zhenshan Liu , Chao Peng , Tongyu Zhu , Qiming Liang |
2021-01-15 | - |
| 33060197 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science David E Gordon , Joseph Hiatt , Mehdi Bouhaddou , Veronica V Rezelj , Svenja Ulferts , Hannes Braberg , Alexander S Jureka , Kirsten Obernier , Jeffrey Z Guo , Jyoti Batra , Robyn M Kaake , Andrew R Weckstein , Tristan W Owens , Meghna Gupta , Sergei Pourmal , Erron W Titus , Merve Cakir , Margaret Soucheray , Michael McGregor , Zeynep Cakir , Gwendolyn Jang , Matthew J O'Meara , Tia A Tummino , Ziyang Zhang , Helene Foussard , Ajda Rojc , Yuan Zhou , Dmitry Kuchenov , Ruth Hüttenhain , Jiewei Xu , Manon Eckhardt , Danielle L Swaney , Jacqueline M Fabius , Manisha Ummadi , Beril Tutuncuoglu , Ujjwal Rathore , Maya Modak , Paige Haas , Kelsey M Haas , Zun Zar Chi Naing , Ernst H Pulido , Ying Shi , Inigo Barrio-Hernandez , Danish Memon , Eirini Petsalaki , Alistair Dunham , Miguel Correa Marrero , David Burke , Cassandra Koh , Thomas Vallet , Jesus A Silvas , Caleigh M Azumaya , Christian Billesbølle , Axel F Brilot , Melody G Campbell , Amy Diallo , Miles Sasha Dickinson , Devan Diwanji , Nadia Herrera , Nick Hoppe , Huong T Kratochvil , Yanxin Liu , Gregory E Merz , Michelle Moritz , Henry C Nguyen , Carlos Nowotny , Cristina Puchades , Alexandrea N Rizo , Ursula Schulze-Gahmen , Amber M Smith , Ming Sun , Iris D Young , Jianhua Zhao , Daniel Asarnow , Justin Biel , Alisa Bowen , Julian R Braxton , Jen Chen , Cynthia M Chio , Un Seng Chio , Ishan Deshpande , Loan Doan , Bryan Faust , Sebastian Flores , Mingliang Jin , Kate Kim , Victor L Lam , Fei Li , Junrui Li , Yen-Li Li , Yang Li , Xi Liu , Megan Lo , Kyle E Lopez , Arthur A Melo , Frank R Moss , Phuong Nguyen , Joana Paulino , Komal Ishwar Pawar , Jessica K Peters , Thomas H Pospiech , Maliheh Safari , Smriti Sangwan , Kaitlin Schaefer , Paul V Thomas , Aye C Thwin , Raphael Trenker , Eric Tse , Tsz Kin Martin Tsui , Feng Wang , Natalie Whitis , Zanlin Yu , Kaihua Zhang , Yang Zhang , Fengbo Zhou , Daniel Saltzberg , QCRG Structural Biology Consortium , Anthony J Hodder , Amber S Shun-Shion , Daniel M Williams , Kris M White , Romel Rosales , Thomas Kehrer , Lisa Miorin , Elena Moreno , Arvind H Patel , Suzannah Rihn , Mir M Khalid , Albert Vallejo-Gracia , Parinaz Fozouni , Camille R Simoneau , Theodore L Roth , David Wu , Mohd Anisul Karim , Maya Ghoussaini , Ian Dunham , Francesco Berardi , Sebastian Weigang , Maxime Chazal , Jisoo Park , James Logue , Marisa McGrath , Stuart Weston , Robert Haupt , C James Hastie , Matthew Elliott , Fiona Brown , Kerry A Burness , Elaine Reid , Mark Dorward , Clare Johnson , Stuart G Wilkinson , Anna Geyer , Daniel M Giesel , Carla Baillie , Samantha Raggett , Hannah Leech , Rachel Toth , Nicola Goodman , Kathleen C Keough , Abigail L Lind , Zoonomia Consortium , Reyna J Klesh , Kafi R Hemphill , Jared Carlson-Stevermer , Jennifer Oki , Kevin Holden , Travis Maures , Katherine S Pollard , Andrej Sali , David A Agard , Yifan Cheng , James S Fraser , Adam Frost , Natalia Jura , Tanja Kortemme , Aashish Manglik , Daniel R Southworth , Robert M Stroud , Dario R Alessi , Paul Davies , Matthew B Frieman , Trey Ideker , Carmen Abate , Nolwenn Jouvenet , Georg Kochs , Brian Shoichet , Melanie Ott , Massimo Palmarini , Kevan M Shokat , Adolfo GarcÃa-Sastre , Jeremy A Rassen , Robert Grosse , Oren S Rosenberg , Kliment A Verba , Christopher F Basler , Marco Vignuzzi , Andrew A Peden , Pedro Beltrao , Nevan J Krogan |
2020-12-04 | - |
| 32353859 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature David E Gordon , Gwendolyn M Jang , Mehdi Bouhaddou , Jiewei Xu , Kirsten Obernier , Kris M White , Matthew J O'Meara , Veronica V Rezelj , Jeffrey Z Guo , Danielle L Swaney , Tia A Tummino , Ruth Hüttenhain , Robyn M Kaake , Alicia L Richards , Beril Tutuncuoglu , Helene Foussard , Jyoti Batra , Kelsey Haas , Maya Modak , Minkyu Kim , Paige Haas , Benjamin J Polacco , Hannes Braberg , Jacqueline M Fabius , Manon Eckhardt , Margaret Soucheray , Melanie J Bennett , Merve Cakir , Michael J McGregor , Qiongyu Li , Bjoern Meyer , Ferdinand Roesch , Thomas Vallet , Alice Mac Kain , Lisa Miorin , Elena Moreno , Zun Zar Chi Naing , Yuan Zhou , Shiming Peng , Ying Shi , Ziyang Zhang , Wenqi Shen , Ilsa T Kirby , James E Melnyk , John S Chorba , Kevin Lou , Shizhong A Dai , Inigo Barrio-Hernandez , Danish Memon , Claudia Hernandez-Armenta , Jiankun Lyu , Christopher J P Mathy , Tina Perica , Kala Bharath Pilla , Sai J Ganesan , Daniel J Saltzberg , Ramachandran Rakesh , Xi Liu , Sara B Rosenthal , Lorenzo Calviello , Srivats Venkataramanan , Jose Liboy-Lugo , Yizhu Lin , Xi-Ping Huang , YongFeng Liu , Stephanie A Wankowicz , Markus Bohn , Maliheh Safari , Fatima S Ugur , Cassandra Koh , Nastaran Sadat Savar , Quang Dinh Tran , Djoshkun Shengjuler , Sabrina J Fletcher , Michael C O'Neal , Yiming Cai , Jason C J Chang , David J Broadhurst , Saker Klippsten , Phillip P Sharp , Nicole A Wenzell , Duygu Kuzuoglu-Ozturk , Hao-Yuan Wang , Raphael Trenker , Janet M Young , Devin A Cavero , Joseph Hiatt , Theodore L Roth , Ujjwal Rathore , Advait Subramanian , Julia Noack , Mathieu Hubert , Robert M Stroud , Alan D Frankel , Oren S Rosenberg , Kliment A Verba , David A Agard , Melanie Ott , Michael Emerman , Natalia Jura , Mark von Zastrow , Eric Verdin , Alan Ashworth , Olivier Schwartz , Christophe d'Enfert , Shaeri Mukherjee , Matt Jacobson , Harmit S Malik , Danica G Fujimori , Trey Ideker , Charles S Craik , Stephen N Floor , James S Fraser , John D Gross , Andrej Sali , Bryan L Roth , Davide Ruggero , Jack Taunton , Tanja Kortemme , Pedro Beltrao , Marco Vignuzzi , Adolfo GarcÃa-Sastre , Kevan M Shokat , Brian K Shoichet , Nevan J Krogan |
2020-07-01 | - |
| 32694731 |
Nat Metab Michael Aregger , Keith A Lawson , Maximillian Billmann , Michael Costanzo , Amy H Y Tong , Katherine Chan , Mahfuzur Rahman , Kevin R Brown , Catherine Ross , Matej Usaj , Lucy Nedyalkova , Olga Sizova , Andrea Habsid , Judy Pawling , Zhen-Yuan Lin , Hala Abdouni , Cassandra J Wong , Alexander Weiss , Patricia Mero , James W Dennis , Anne-Claude Gingras , Chad L Myers , Brenda J Andrews , Charles Boone , Jason Moffat |
2020-06-01 | - |
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31806350 |
Mol. Cell Guangyan Miao , Yujie Zhang , Di Chen , Hong Zhang |
2020-02-06 | - |
| 29576527 |
Mol Cell Dominika Kwasna , Syed Arif Abdul Rehman , Jayaprakash Natarajan , Stephen Matthews , Ross Madden , Virginia De Cesare , Simone Weidlich , Satpal Virdee , Ivan Ahel , Ian Gibbs-Seymour , Yogesh Kulathu |
2018-04-05 | - |
| 29507755 |
Cell Discov Yanan Yue , Jun Liu , Xiaolong Cui , Jie Cao , Guanzheng Luo , Zezhou Zhang , Tao Cheng , Minsong Gao , Xiao Shu , Honghui Ma , Fengqin Wang , Xinxia Wang , Bin Shen , Yizhen Wang , Xinhua Feng , Chuan He , Jianzhao Liu |
2018-01-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26949251 |
The cell proliferation antigen Ki-67 organises heterochromatin. Elife Michal Sobecki , Karim Mrouj , Alain Camasses , Nikolaos Parisis , Emilien Nicolas , David Llères , François Gerbe , Susana Prieto , Liliana Krasinska , Alexandre David , Manuel Eguren , Marie-Christine Birling , Serge Urbach , Sonia Hem , Jérôme Déjardin , Marcos Malumbres , Philippe Jay , Vjekoslav Dulic , Denis Lj Lafontaine , Robert Feil , Daniel Fisher |
2016-01-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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