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23332 CLASP1

23332

CLASP1

cytoplasmic linker associated protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition cytoplasmic linker associated protein 1

研究结论

Date Results Publications
2017-08-05 12:56:00 Prickle1 localized to the membrane through its farnesyl moiety, and the membrane localization was necessary for Prickle1 to regulate migration, to bind to CLASPs and LL5beta, and to promote microtubule targeting of focal adhesions. 27378169
2017-06-24 10:08:00 catastrophe inhibition by SLAIN2 and CLASP1 supports mesenchymal cell shape in soft 3D matrices by enabling microtubules to perform a load-bearing function. 27939686
2015-06-27 14:09:00 Acute silencing of CLASP1, a +TIP that participates in microtubule stabilization at the cell periphery, impairs trypomastigote internalization without diminishing the capacity for calcium-regulated lysosome exocytosis. 23107073
2014-08-09 11:38:00 Propose that CLASPs couple microtubule organization, vesicle transport and cell interactions with the ECM, establishing a local secretion pathway that facilitates focal adhesion turnover by severing cell-matrix connections. 24859005
2014-04-05 13:15:00 our data suggest a model for mitotic spindle positioning in which RanGTP and CLASP1 cooperate to align the spindle along the long axis of the dividing cell. 23783028

名称对应

Type IDs
Synonymous MAST1
Gene
UniProtKB-ID: CLAP1_HUMAN
UniprotKB: Q7Z460
UniParc: UPI0000ED8F58, UPI0000F095C6, UPI00001A8BFF, UPI0000695D7F, UPI000189A8B8
EMBL: BC132723, AC079449, AB014522, BC112940, BC144107, AC012447, AJ288057, CR933722, AC018737, AC013399, AF347693, BC032563
Ensembl: ENSG00000074054
KO: hsa:23332
Nucleutide sequences
EMBL-CDS: AAI32724.1, AAX88872.1, AAI44108.1, AAI12941.1, AAH32563.1, CAC35156.1, CAI46251.1, BAA31597.1, AAQ15051.1
Ensembl_TRS: ENST00000541377, ENST00000409078, ENST00000646274, ENST00000263710, ENST00000397587
Protein sequencees
Ensembl_PRO: ENSP00000386442, ENSP00000441625, ENSP00000263710, ENSP00000380717, ENSP00000496269
RefSeq: XP_016859174.1, XP_011509151.1, XP_016859172.1, NP_001135745.1, XP_016859173.1, XP_016859148.1, NP_001193980.1, XP_016859153.1, NP_001364934.1, XP_006712445.1, XP_016859150.1, XP_016859170.1, NP_001364933.1, XP_016859177.1, XP_016859160.1, NP_001364932.1, NP_056097.1, XP_016859178.1, XP_016859155.1, XP_016859147.1, NP_001135746.1, XP_016859168.1, XP_016859180.1, XP_016859157.1, XP_016859156.1, XP_016859159.1, XP_011509150.1, XP_016859163.1, XP_016859151.1, XP_006712446.1, XP_016859154.1, XP_016859165.1, XP_016859146.1, XP_016859176.1, XP_016859152.1, XP_016859167.1, XP_016859162.1, XP_016859179.1, XP_016859164.1, XP_016859158.1, XP_016859149.1, XP_006712444.1, XP_006712448.1, XP_016859171.1, XP_006712440.1, XP_016859161.1, XP_016859175.1, XP_016859166.1, XP_016859169.1
Others
UniRef100: UniRef100_Q7Z460
UniRef90: UniRef90_Q7Z460
UniRef50: UniRef50_Q7Z460
UniGene: Hs.469840, Hs.708183

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