| Type | Description |
|---|---|
| Definition | sialic acid binding Ig-like lectin H |
| Date | Results | Publications |
|---|---|---|
| 2018-11-03 12:00:00 | Synthesized branched sialylated glycan clusters interacted with sialic acid-binding immunoglobulin-like lectin H (Siglec-H), which is known to be a microglia-specific molecule. | 30033944 |
| 2018-06-09 11:29:00 | The Siglec-H is specifically expressed by microglia in the steady state developing CNS and adult mice, except for in the choroid plexus | 28836308 |
| 2017-07-29 10:36:00 | These results show that Siglec-H normally serves as a modulator of type I IFN responses after infection with a persistent virus and thereby prevents induction of autoimmune disease | 27377589 |
| 2014-06-07 11:04:00 | We found that lack of SiglecH enhanced IFN-I responses to viral infection, regardless of whether Plasmacytoid dendritic cells were depleted | 24683186 |
| 2014-05-03 10:50:00 | Siglec-H deficiency induced a significant increase in serum IFNalpha levels following systemic MCMV infection. Although Siglec-H modulates anti-viral IFNalpha production, the control of viral replication was unchanged in vivo. | 24086137 |
| Type | IDs |
|---|---|
| Synonymous | 6430529G09Rik, Siglec-H |
| Gene |
UniProtKB-ID:
A0A4W8_MOUSE,
G3X9N0_MOUSE,
A0A4X5_MOUSE,
Q3Y597_MOUSE,
Q4QQK7_MOUSE,
B7ZMQ5_MOUSE
UniprotKB:
A0A4W8,
G3X9N0,
A0A4X5,
Q3Y597,
Q4QQK7,
B7ZMQ5
UniParc:
UPI000011C9A3,
UPI000024ED30,
UPI00001C3C9D,
UPI000011C94C,
UPI00005AB17E,
UPI000011C977
EMBL:
AK045719,
AC160534,
DQ208935,
BC144741,
DQ157764,
BC120501,
BC098229,
AK032377
Ensembl:
ENSMUSG00000051504
KO:
mmu:233274
|
| Nucleutide sequences |
EMBL-CDS:
BAC27845.1,
BAC32469.1,
AAZ81614.1,
ABB20891.1,
AAI20502.1,
AAH98229.1,
AAI44742.1
Ensembl_TRS:
ENSMUST00000094360,
ENSMUST00000060416,
ENSMUST00000171077,
ENSMUST00000173835,
ENSMUST00000121492
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000091920,
ENSMUSP00000058875,
ENSMUSP00000130943,
ENSMUSP00000134721,
ENSMUSP00000113665
RefSeq:
XP_011249161.1,
XP_011249159.1,
XP_011249160.1,
XP_036008873.1,
XP_006540890.2,
XP_036008871.1,
NP_001297669.1,
XP_036008870.1,
XP_036008869.1,
XP_030098329.1,
XP_036008867.1,
NP_848821.2,
XP_036008868.1,
XP_036008866.1,
XP_036008872.1,
NP_001297667.1
|
| Others |
UniRef100:
UniRef100_B7ZMQ5,
UniRef100_Q4QQK7,
UniRef100_Q3Y597,
UniRef100_A0A4W8,
UniRef100_G3X9N0
UniRef90:
UniRef90_B7ZMQ5,
UniRef90_Q3Y597
UniRef50:
UniRef50_Q3Y597,
UniRef50_B7ZMQ5
UniGene:
Mm.44425
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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