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23327 NEDD4L

23327

NEDD4L

neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

protein-coding

Homo sapiens

基因描述

Type Description
Definition neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

研究结论

Date Results Publications
2021-03-20 13:29:00 NEDD4L-mediated LTF protein degradation limits ferroptosis. 32811647
2021-03-13 13:16:00 Novel genetic variants in KIF16B and NEDD4L in the endosome-related genes are associated with nonsmall cell lung cancer survival. 31618441
2021-01-16 15:59:00 NEDD4L downregulates autophagy and cell growth by modulating ULK1 and a glutamine transporter. 31959741
2021-01-09 13:33:00 USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L-SMAD pathway. 33106424
2021-01-02 12:53:00 Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. 33045005

名称对应

Type IDs
Synonymous NEDD4-2, NEDD4.2, PVNH7, RSP5, hNEDD4-2
Gene
UniProtKB-ID: NED4L_HUMAN, A0A024R281_HUMAN, B7Z6K0_HUMAN, A0A024R2A4_HUMAN, B7Z2P9_HUMAN
UniprotKB: Q96PU5, A0A024R281, B7Z6K0, A0A024R2A4, B7Z2P9
UniParc: UPI00005B730C, UPI0000201DDD, UPI000191522F, UPI0001914B73, UPI0000072494, UPI00000731AF, UPI000058E3AE, UPI000058E4EA, UPI000006DE15, UPI000058E4EB
EMBL: DQ181796, AY112985, BC032597, AC107896, AY312514, AF385931, AK300444, AY112983, AB071179, AF210730, BC019345, BC000621, AL137469, AB007899, AY112984, AC090236, AK294963, AC015988, CH471096
Ensembl: ENSG00000049759
KO: hsa:23327
Nucleutide sequences
EMBL-CDS: BAA23711.1, AAH19345.1, AAM76730.1, AAM76728.1, CAB70754.1, ABA10330.1, AAG43524.1, AAH00621.2, AAP75706.1, AAM76729.1, BAB69424.1, AAH32597.1, EAW63065.1, AAM46208.1, EAW63075.1, EAW63067.1, BAH13286.1, EAW63073.1, EAW63072.1, BAH11935.1
Gene_ORFName: hCG_23086, hCG_23086
Ensembl_TRS: ENST00000586263, ENST00000382850, ENST00000435432, ENST00000431212, ENST00000456173, ENST00000256830, ENST00000357895, ENST00000356462, ENST00000456986, ENST00000400345
Protein sequencees
Ensembl_PRO: ENSP00000256830, ENSP00000383199, ENSP00000372301, ENSP00000393395, ENSP00000405440, ENSP00000350569, ENSP00000348847, ENSP00000411947, ENSP00000389406, ENSP00000468546
RefSeq: XP_016881165.1, NP_001230889.1, XP_006722487.2, XP_024306903.1, XP_016881169.1, NP_001138441.1, XP_024306904.1, NP_001138437.1, XP_006722488.2, XP_016881167.1, NP_001138442.1, XP_006722484.2, NP_001138440.1, XP_006722489.1, NP_001138439.1, XP_024306901.1, XP_024306905.1, XP_005266717.2, XP_006722491.1, XP_011524189.1, XP_016881168.1, XP_006722493.1, XP_016881170.1, XP_016881166.1, NP_001138438.1, XP_024306899.1, XP_024306897.1, NP_001138436.1, XP_024306902.1, XP_024306900.1, XP_024306898.1, XP_005266715.2, NP_056092.2, NP_001138443.1, XP_005266720.2
Others
UniRef100: UniRef100_A0A024R281, UniRef100_B7Z2P9, UniRef100_B7Z6K0, UniRef100_A0A1B0GVY1, UniRef100_Q96PU5
UniRef90: UniRef90_Q96PU5, UniRef90_B7Z2P9, UniRef90_A0A024R281, UniRef90_B7Z6K0
UniRef50: UniRef50_U3I9E4, UniRef50_Q96PU5, UniRef50_Q5RBF2, UniRef50_A0A3Q1M231
UniGene: Hs.185677
CCDS: CCDS45873.1, CCDS45874.1, CCDS59323.1, CCDS45876.1, CCDS45875.1, CCDS58632.1, CCDS45872.1

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