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233222 Mrgpra3

233222

Mrgpra3

MAS-related GPR, member A3

protein-coding

Mus musculus

基因描述

Type Description
Definition MAS-related GPR, member A3

研究结论

Date Results Publications
2021-04-13 10:08:00 Molecular Signature of Pruriceptive MrgprA3(+) Neurons. 32234460
2018-06-23 11:09:00 Results showed that the scratching bouts induced by chloroquine increased significantly under the acetone-ether-water (AEW) chronic pruritus; the density of MrgprA3 sensory fibers in the AEW-treated skin area and the number of MrgprA3 neurons in dorsal root ganglia from the AEW model mice also increased significantly. Further analysis showed that the MrgprA3 in mRNA level was also increased after AEW treatment. 29064954
2016-12-24 11:38:00 This study demonstrated that MrgprA3+ neurons have lower excitability than the same size MrgprA3--non-Dil and MrgprA3--Dil neurons. MrgprA3+ neurons exhibit decreased AP firing activity. 26874069
2014-05-24 11:18:00 showed that both MRGPRA3+ and MRGPRD+ neurons from hapten-challenged mice displayed a significantly more depolarized resting membrane potential, decreased rheobase, and greater number of action potentials at twice rheobase compared with neurons 24549959
2013-03-23 11:57:00 This study demonistrated that MrgprA3 expression defines a specific population of itch-mediating neurons and determined the molecular identity and cellular properties of these neurons. 23263443

名称对应

Type IDs
Synonymous Mrga3
Gene
UniProtKB-ID: MRGA3_MOUSE, H3BKL3_MOUSE
UniprotKB: Q91WW3, H3BKL3
UniParc: UPI000154BB94, UPI000002942F
EMBL: AY042193, AC138678, AC147232
Ensembl: ENSMUSG00000078698
KO: mmu:233222
Nucleutide sequences
EMBL-CDS: AAK91789.1
Ensembl_TRS: ENSMUST00000176369
Protein sequencees
Ensembl_PRO: ENSMUSP00000135437
RefSeq: NP_694707.2
Others
UniRef100: UniRef100_Q91WW3
UniRef90: UniRef90_Q91WW3
UniRef50: UniRef50_Q91WW3
UniGene: Mm.240142

全选

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研究热度

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