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23315 SLC9A8

23315

SLC9A8

solute carrier family 9 member A8

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 9 member A8

研究结论

Date Results Publications
2017-07-08 11:52:00 work has uncovered a crucial role of NHE8 in acrosome biogenesis and suggests that some forms of human globozoospermia might be caused by a loss of function of this Na(+)/H(+) exchanger. 28476888
2016-05-28 12:25:00 NHE8 is expressed in goblet cells, and the inflammatory cytokine TNF-alpha downregulates NHE8 expression by a transcriptional mechanism. 26564720
2012-02-25 10:47:00 Exonic mutations in NHE8 cannot account for congenital sodium diarrhea. 21666503
2011-03-26 10:23:00 This review defines NHE6-9 as organellar NHEs that are fairly dynamic, implying that they are subjected to intracellular trafficking and thus they continuously shuttle between organelles and the plasma membrane. 21171650
2011-03-19 10:13:00 These data point to a role for the ion exchange activity of NHE8 being required to maintain endosome morphology. 20719963

名称对应

Type IDs
Synonymous NHE-8, NHE8
Gene
UniProtKB-ID: SL9A8_HUMAN, B4DIX7_HUMAN
UniprotKB: Q9Y2E8, B4DIX7
UniParc: UPI00017A72E9, UPI00017A7E08, UPI00001C2035
EMBL: AK295822, AK131001, AL031685, AL162615, AK300318, CH471077, BC112213, AB023156, CR749638
Ensembl: ENSG00000197818
KO: hsa:23315
Nucleutide sequences
EMBL-CDS: EAW75649.1, CAH18432.1, BAC85475.1, BAG62070.1, BAA76783.2, AAI12214.1, BAG58639.1
Ensembl_TRS: ENST00000361573, ENST00000417961
Protein sequencees
Ensembl_PRO: ENSP00000416418, ENSP00000354966
RefSeq: NP_056081.1, XP_011527047.1, XP_016883243.1, XP_011527044.1, XP_011527040.1, XP_011527038.1, XP_016883244.1, XP_011527041.1, XP_006723819.1, XP_011527043.1, XP_011527042.1, XP_016883245.1, XP_011527039.1, NP_001247420.1, XP_011527045.1, XP_011527046.1
Others
UniRef100: UniRef100_Q9Y2E8, UniRef100_B4DIX7
UniRef90: UniRef90_B4DIX7, UniRef90_Q9Y2E8
UniRef50: UniRef50_A0A2L0B5E3, UniRef50_Q9Y2E8
UniGene: Hs.444202
CCDS: CCDS13421.1, CCDS58774.1

全选

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