| Type | Description |
|---|---|
| Definition | non-SMC condensin II complex subunit D3 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 13:33:00 | NCAPD2 and NCAPD3 expression levels have been confirmed to be significantly up-regulated in the intestinal mucosa of patients with active ulcerative colitis. In vitro, the data suggested that silencing NACPD2 and NACPD3 could depress the expression of IL-1beta, IL-6 and TNF-alpha. Further, knockdown of NACPD2 and NACPD3 could remarkably suppress IKK nucleation and NF-kappaB volume. | 31885422 |
| 2017-11-11 10:07:00 | Condensin II(CAP-D3 and CAP-H2) and GAIT subunits associate with L1 RNA in a co-dependent manner, independent of IFN-gamma. These findings suggest that cooperation between the Condensin II and GAIT complexes may facilitate a novel mechanism of L1 repression, thus contributing to the maintenance of genome stability in somatic cells | 29028794 |
| 2015-08-08 11:00:00 | CAP-D3 down-regulates transcription of genes that encode amino acid transporters (SLC7A5 and SLC3A2) to promote bacterial autophagy by colon epithelial cells. | 25701737 |
| 2011-06-18 11:08:00 | The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II. | 21498573 |
| 2010-06-30 22:06:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | CAP-D3, CAPD3, MCPH22, hCAP-D3, hHCP-6, hcp-6 |
| Gene |
UniProtKB-ID:
CNDD3_HUMAN
UniprotKB:
P42695
UniParc:
UPI00001C1EFE
EMBL:
AF070553,
D29954,
BC098398,
AP001775,
CH471065
Ensembl:
ENSG00000151503
KO:
hsa:23310
|
| Nucleutide sequences |
EMBL-CDS:
BAA06224.1,
AAC28639.1,
EAW67824.1,
AAH98398.1
Ensembl_TRS:
ENST00000534548
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000433681
RefSeq:
NP_056076.1,
NP_001358994.1,
NP_001358998.1,
NP_001358999.1,
NP_001358997.1
|
| Others |
UniRef100:
UniRef100_P42695
UniRef90:
UniRef90_P42695
UniRef50:
UniRef50_P42695
UniGene:
Hs.438550
CCDS:
CCDS31723.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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