| Type | Description |
|---|---|
| Definition | free fatty acid receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:38:00 | Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease. | 32093510 |
| 2021-03-06 13:27:00 | Acetate protects against intestinal ischemia-reperfusion injury independent of its cognate free fatty acid 2 receptor. | 32725930 |
| 2020-10-31 13:13:00 | Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2. | 31876919 |
| 2020-10-24 14:12:00 | Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasome complex to prevent Salmonella infection. | 32991574 |
| 2020-07-11 10:10:00 | Loss of Ffar2 promoted colon tumorigenesis in susceptible mice by reducing gut barrier integrity, increasing bacteria in tumors, promoting exhaustion of CD8+ T cells, and over-activating dendritic cells (DCs). DCs from ApcMin/+Ffar2-/- mice had an altered state of activation, increased death, and higher production of IL27. Antibodies against IL27 and agonists of Ffar2 reduced tumorigenesis in these mice. | 31917258 |
| Type | IDs |
|---|---|
| Synonymous | GPCR43, Gpr43 |
| Gene |
UniProtKB-ID:
FFAR2_MOUSE
UniprotKB:
Q8VCK6
UniParc:
UPI00000252AE
EMBL:
AF545043,
AK078861,
BC019570
Ensembl:
ENSMUSG00000051314
KO:
mmu:233079
|
| Nucleutide sequences |
EMBL-CDS:
BAC37425.1,
AAH19570.1,
AAO16236.1
Ensembl_TRS:
ENSMUST00000053156,
ENSMUST00000163504,
ENSMUST00000168528
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129398,
ENSMUSP00000052600,
ENSMUSP00000127758
RefSeq:
XP_011248850.1,
NP_001161981.1,
XP_011248855.1,
XP_011248854.1,
NP_001161984.1,
XP_011248856.1,
NP_001161982.1,
NP_001161983.1,
XP_011248851.1,
NP_666299.1
|
| Others |
UniRef100:
UniRef100_Q8VCK6
UniRef90:
UniRef90_Q8VCK6
UniRef50:
UniRef50_O15552
UniGene:
Mm.97338
CCDS:
CCDS21111.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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