| Type | Description |
|---|---|
| Definition | WD repeat domain 62 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:13:00 | WDR62 is a novel participator in spindle migration and asymmetric cytokinesis during mouse oocyte meiotic maturation. | 31836472 |
| 2020-10-24 13:59:00 | The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development. | 31816041 |
| 2020-06-27 10:53:00 | WDR62 is involved in spindle assembly by interacting with CEP170 in spermatogenesis | 31533924 |
| 2019-07-13 11:14:00 | Study in mutant mice and human cerebral organoids showed that WDR62 deletion resulted in a reduction in the size of mouse brains and organoids due to the disruption of neural progenitor cells. WDR62 interacts with and promotes CEP170 localization to the basal body of primary cilium, where CEP170 recruits KIF2A to disassemble cilium. | 31197141 |
| 2019-01-19 11:44:00 | Wdr62 is involved in meiotic initiation via activating JNK signaling, which displays a novel mechanism for regulating meiotic initiation, and mutation of WDR62 is one of the potential etiologies of premature ovarian insufficiency in humans. | 30102701 |
| Type | IDs |
|---|---|
| Synonymous | 2310038K02Rik, b2b1508Clo |
| Gene |
UniProtKB-ID:
E9QK36_MOUSE
UniprotKB:
E9QK36
UniParc:
UPI00006056B4
EMBL:
AC149067
Ensembl:
ENSMUSG00000037020
KO:
mmu:233064
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000108190
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103825
RefSeq:
XP_030098315.1,
XP_030098316.1,
XP_036008850.1,
XP_011248846.1,
XP_006539940.1,
XP_011248844.1,
XP_011248845.1,
NP_666298.4,
XP_011248842.1,
XP_036008851.1,
XP_011248847.1,
XP_011248843.1,
XP_006539943.1,
XP_030098317.1,
XP_036008852.1,
XP_006539938.1,
XP_006539944.1
|
| Others |
UniRef100:
UniRef100_E9QK36
UniRef90:
UniRef90_Q3U3T8
UniRef50:
UniRef50_O43379
UniGene:
Mm.271677
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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