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232975 Atp1a3

232975

Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

protein-coding

Mus musculus

基因描述

Type Description
Definition ATPase, Na+/K+ transporting, alpha 3 polypeptide

研究结论

Date Results Publications
2020-10-10 13:00:00 ATP1A3 mutation as a candidate cause of autosomal dominant cone-rod dystrophy. 32440726
2019-10-12 12:09:00 Na(+)/K(+)-ATPase alpha3 does not reside within the core circadian molecular clockwork, but Myk/+ mice exhibit concomitant disruption in circadian rhythms and mood. The Myshkin model demonstrates profound circadian and light-responsive behavioral alterations independent of molecular clock disruption. 28689605
2019-09-21 12:07:00 The animal model containing a E815K mutation in ATP1A3, manifests clinical and neurophysiological features of the most severe form of alternating hemiplegia of childhood. 30071271
2019-03-02 11:27:00 the neuronal specific alpha3 (alpha3)-subunit of the plasma membrane enzyme Na, K-ATPase (NKA) is a new binding partner of sAPPalpha. 28983842
2018-05-19 11:36:00 A heterozygous knock-in mouse harboring the D801Y mutation in ATP1A3 was generated. This mice displayed hyperactivity, increased sensitivity to chemically induced epileptic seizures and cognitive deficits. The findings reveal the functional significance of ATP1A3 gene in the control of spatial learning and memory and suggest a link to GABA transmission. 27549929

名称对应

Type IDs
Synonymous Atpa-2
Gene
UniProtKB-ID: AT1A3_MOUSE, Q8VCE0_MOUSE, Q8R0E8_MOUSE, A0A0G2JGX4_MOUSE
UniprotKB: Q6PIC6, Q8VCE0, Q8R0E8, A0A0G2JGX4
UniParc: UPI0000001528, UPI00000E6A4E, UPI0000F4FC6A, UPI00000288C4
EMBL: AC125468, BC034645, BC042894, BC027000, BC020177, BC037206
Ensembl: ENSMUSG00000040907
KO: mmu:232975
Nucleutide sequences
EMBL-CDS: AAH42894.1, AAH34645.1, AAH37206.1, AAH20177.1, AAH27000.1
Ensembl_TRS: ENSMUST00000080882, ENSMUST00000102858, ENSMUST00000196684
Protein sequencees
Ensembl_PRO: ENSMUSP00000079691, ENSMUSP00000099922, ENSMUSP00000143735
RefSeq: NP_001277398.1, XP_011248820.1, NP_001361556.1, XP_011248821.1
Others
UniRef100: UniRef100_Q6PIC6, UniRef100_Q8VCE0, UniRef100_A0A0G2JGX4, UniRef100_Q8R0E8
UniRef90: UniRef90_Q6PIC6, UniRef90_A0A286ZRK2, UniRef90_A0A0G2JGX4, UniRef90_Q8R0E8
UniRef50: UniRef50_P50993, UniRef50_P06685
UniGene: Mm.44101
CCDS: CCDS20969.2

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研究热度

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