| Type | Description |
|---|---|
| Definition | mahogunin ring finger 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-28 12:04:00 | epletion of MGRN1 activity may hamper physiologically important processes like mitochondrial movement in neuronal processes and intracellular transport of ligands through the endosomal pathway thereby contributing to the pathogenesis of neurodegeneration in certain types of prion diseases | 28902452 |
| 2018-04-07 11:25:00 | In a heterologous expression system, MC1R-dependent Arrestins B ubiquitination was enhanced by overexpression of MGRN1 and was impaired by siRNA-mediated MGRN1 knockdown thus pointing to MGRN1 as the responsible E3-ligase. | 28947386 |
| 2018-02-10 10:29:00 | Hypomethylation of CpG sites in RPTOR, MGRN1 and RAPSN in blood is associated with breast cancer. | 27577081 |
| 2017-10-07 11:16:00 | Regulation of Mfn1 by MGRN1 and the proteasome modulates mitochondrial fusion. | 27713096 |
| 2017-09-09 10:24:00 | With aging, the neuroprotective e3 ligase MGRN1 relocates from the cytosol to the nucleus of neurons, where it associates with chromatin and potentiates the cellular response to proteotoxic stress. This nuclear shift is due to a proteasome impairment dependent increase of a monoubiquitinated form of MGRN1. | 28475871 |
| Type | IDs |
|---|---|
| Synonymous | RNF156 |
| Gene |
UniProtKB-ID:
MGRN1_HUMAN
UniprotKB:
O60291
UniParc:
UPI0000409A51,
UPI000018CE7F,
UPI0001894762,
UPI0001894763
EMBL:
AB011116,
BC050389,
EF471397,
EF471398,
AC023830
Ensembl:
ENSG00000102858
KO:
hsa:23295
|
| Nucleutide sequences |
EMBL-CDS:
ABO69623.2,
BAA25470.1,
ABO69624.2,
AAH50389.1
Ensembl_TRS:
ENST00000586183,
ENST00000262370,
ENST00000415496,
ENST00000588994,
ENST00000399577
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000465860,
ENSP00000468819,
ENSP00000262370,
ENSP00000393311,
ENSP00000382487
RefSeq:
NP_001135762.1,
NP_001135761.2,
NP_001135763.2,
NP_056061.1
|
| Others |
UniRef100:
UniRef100_O60291
UniRef90:
UniRef90_O60291
UniRef50:
UniRef50_O60291
UniGene:
Hs.526494
CCDS:
CCDS42115.1,
CCDS45401.2,
CCDS59256.1,
CCDS45402.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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