| Type | Description |
|---|---|
| Definition | F-box and WD repeat domain containing 11 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:55:00 | findings support the role of FBXW11 in multiple developmental processes, including those involving the brain, eye, digits, and jaw | 31402090 |
| 2020-03-28 10:57:00 | Fbxw11 expression is upregulated in patients with ALL. High levels of Fbxw11 expression stimulate the proliferation of L1210 lymphocytic leukemia cells in vitro and promote tumor formation in vivo by regulating the cell cycle. Most importantly, activation of both the NF-kappaB and beta-catenin/TCF signaling pathways is involved in this process. | 29555946 |
| 2020-02-22 12:07:00 | USP9X promotes tumorigenesis and FBXW11 suppresses tumorigenesis through PTENalpha/beta. | 31685992 |
| 2019-01-09 15:28:00 | beta-TrCP was identified as a novel interacting partner of ASK1 that is capable of ubiquitinating and degrading ASK1 through the ubiquitin-proteasome system. These findings suggest that beta-TrCP is capable of suppressing oxidative stress-induced caspase 3-dependent apoptosis through suppression of ASK1. | 30031111 |
| 2015-02-14 12:06:00 | SCF(FBXW11) bound, polyubiquitylated, and destabilized RAPGEF2, a guanine nucleotide exchange factor that activates the small GTPase RAP1 | 25332235 |
| Type | IDs |
|---|---|
| Synonymous | BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos |
| Gene |
UniProtKB-ID:
FBW1B_HUMAN,
B4DH70_HUMAN
UniprotKB:
Q9UKB1,
B4DH70
UniParc:
UPI000002AA01,
UPI00005A07E4,
UPI000012ADB8,
UPI000000129E
EMBL:
BC026213,
AK314999,
AB033281,
AK294956,
AB014596,
AB033280,
AF176022,
AB033279
Ensembl:
ENSG00000072803
KO:
hsa:23291
|
| Nucleutide sequences |
EMBL-CDS:
BAA92330.1,
BAA92331.1,
BAA92329.1,
AAF04528.1,
AAH26213.1,
BAA31671.1,
BAG37495.1,
BAG58031.1
Ensembl_TRS:
ENST00000265094,
ENST00000393802,
ENST00000296933
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265094,
ENSP00000296933,
ENSP00000377391
RefSeq:
XP_005265914.1,
NP_387449.2,
NP_001365909.1,
NP_001365903.1,
NP_001365907.1,
XP_016864768.1,
NP_001365905.1,
NP_001365908.1,
NP_001365904.1,
NP_387448.2,
NP_001365906.1,
NP_036432.2
|
| Others |
UniRef100:
UniRef100_A0A5F4BPT4,
UniRef100_Q9UKB1
UniRef90:
UniRef90_Q9UKB1
UniRef50:
UniRef50_Q9Y297
UniGene:
Hs.484138
CCDS:
CCDS34289.1,
CCDS47340.1,
CCDS47341.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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