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232889 Pla2g4c

232889

Pla2g4c

phospholipase A2, group IVC (cytosolic, calcium-independent)

protein-coding

Mus musculus

基因描述

Type Description
Definition phospholipase A2, group IVC (cytosolic, calcium-independent)

研究结论

Date Results Publications
2019-02-09 11:59:00 Validation of differentially expressed genes (DEGs) by quantitative RT-PCR showed a significant increase in PLA2 group 4c (Pla2g4c)/COX-2 (Ptgs2)/PGD2 synthase 2 (Hpgds) axis. PGD2 level in bronchoalveolar fluids of the OA-challenged mice was significantly increased. A 24-h incubation of BSM tissues with PGD2 caused a hyperresponsiveness to acetylcholine in naive control mice. 30161143
2012-03-31 11:14:00 results link cytokine-mediated alterations in cPLA2gamma gene expression with allergic asthma and outline a complex regulatory mechanism 22082005
2011-03-05 11:09:00 Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation. 20817734
2010-08-16 11:11:00 cPLA(2) has a role in the induction of cell autonomous cellular immunity to Chlamydia 20452986
2010-01-21 00:00:00 iPLA2gamma has roles in the lipid plasticity of myocardium, in generating signaling metabolites, and in modulating energy storage and utilization in myocardium in different metabolic contexts 17213206

名称对应

Type IDs
Synonymous D7Ertd445e
Gene
UniProtKB-ID: PA24C_MOUSE
UniprotKB: Q64GA5
UniParc: UPI000003F54C, UPI0000428F1C
EMBL: AK136143, AY694793, BC145767, BC117808, AC161792, BC129974, AK136098, AK162196, BC138548, BC117809, AK145339, BC054740
Ensembl: ENSMUSG00000033847
KO: mmu:232889
Nucleutide sequences
EMBL-CDS: AAI17809.1, BAE22819.1, AAI45768.1, AAH54740.1, AAU14177.1, AAI38549.1, AAI17810.1, BAE22843.1, AAI29975.1, BAE26375.1, BAE36785.1
Ensembl_TRS: ENSMUST00000108528, ENSMUST00000043612, ENSMUST00000167232
Protein sequencees
Ensembl_PRO: ENSMUSP00000043672, ENSMUSP00000127060, ENSMUSP00000104168
RefSeq: XP_006539868.1, XP_036008837.1, NP_001161976.1, NP_001004762.1
Others
UniRef100: UniRef100_Q64GA5
UniRef90: UniRef90_Q64GA5
UniRef50: UniRef50_Q64GA5
UniGene: Mm.223639
CCDS: CCDS39771.1, CCDS52027.1

全选

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