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23283 CSTF2T

23283

CSTF2T

cleavage stimulation factor subunit 2 tau variant

protein-coding

Homo sapiens

基因描述

Type Description
Definition cleavage stimulation factor subunit 2 tau variant

研究结论

Date Results Publications
2017-10-07 12:53:00 CSTF2tau binds many previously not recognized RNAs including histone, snoRNA and snRNAs. CSTF2tau-binding is associated with internal oligoadenylation resulting in shortened snRNA isoforms subjected to rapid degradation. CSTF2tau controls the abundance of snRNAs resulting in alternative splicing of several RNAs with critical roles in tumorigenesis and cardiac function. 28334977
2014-01-18 11:10:00 CstF64 and CstF64tau modulate one another's expression and play overlapping as well as distinct roles in regulating global alternative polyadenylation profiles. 24149845
2010-01-21 13:04:00 Studied expression levels of CstF-64 in EV71-infected cells; showed reduction of CstF-64 during virus infection correlated with production of viral 3C(pro). CstF-64 was cleaved in vitro by 3C(pro) not by mutant 3C(pro) variants. 19779565
2010-01-21 00:00:00 Radiation hybrid mapping places the human tauCstF-64 gene at 10q22-q23, which is the site of a translocation that has been associated with human neurological problems and male infertility. 12408968
2010-01-21 00:00:00 upstream element in human papillomavirus type 16 interacted specifically with CstF-64, hnRNP C1/C2 & polypyrimidine tract binding protein, suggesting these factors were enhancing or regulating polyadenylation at the HPV-16 early polyadenylation signal 15767428

名称对应

Type IDs
Synonymous CstF-64T
Gene
UniProtKB-ID: CSTFT_HUMAN
UniprotKB: Q9H0L4
UniParc: UPI0000073CA9
EMBL: AK222574, AK314318, AB014589, CH471083, AL136747, AY130299, BC028239
Ensembl: ENSG00000177613
KO: hsa:23283
Nucleutide sequences
EMBL-CDS: BAG36966.1, AAN05429.1, BAA31664.1, EAW54142.1, BAD96294.1, AAH28239.1, CAB66681.1
Ensembl_TRS: ENST00000331173
Protein sequencees
Ensembl_PRO: ENSP00000332444
RefSeq: NP_056050.1
Others
UniRef100: UniRef100_Q9H0L4
UniRef90: UniRef90_Q9H0L4
UniRef50: UniRef50_P33240
UniGene: Hs.591358
CCDS: CCDS7245.1

全选

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