| Type | Description |
|---|---|
| Definition | NLR family, pyrin domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 10:06:00 | Activation of the NLRP2 inflammasome leads to activation of dorsal root ganglion neurons and subsequent development of pain hypersensitivity. | 31162334 |
| 2019-05-18 11:27:00 | NLRP2 might be a potential target for developing effective therapeutic strategy to prevent Nonalcoholic fatty liver disease progression. | 30454891 |
| 2019-03-23 12:10:00 | Study shownd that apoptosis signal-regulating kinase 1 (ASK1) silencing and ASK1 inhibition reduced ischemic injury-induced nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 2 inflammasomes in the brain and astrocyte cell line, respectively. | 30172704 |
| 2018-11-17 12:24:00 | female mice lacking NLRP2 are subfertile because of early embryonic loss and the production of fewer offspring that have a wide array of developmental phenotypes and abnormal DNA methylation at imprinted loci. | 28317850 |
| 2018-04-28 10:53:00 | NLRP2 interacts with FAF1 under normal physiological conditions | 28630100 |
| Type | IDs |
|---|---|
| Synonymous | E330007A02Rik, NBS1, Nalp2, PAN1, PYPAF2 |
| Gene |
UniProtKB-ID:
Q4PLS0_MOUSE
UniprotKB:
Q4PLS0
UniParc:
UPI00003575BE
EMBL:
AC155171,
DQ066881
Ensembl:
ENSMUSG00000035177
KO:
mmu:232827
|
| Nucleutide sequences |
EMBL-CDS:
AAY68479.1
Ensembl_TRS:
ENSMUST00000045022
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000045077
RefSeq:
NP_808358.2
|
| Others |
UniRef100:
UniRef100_Q4PLS0
UniRef90:
UniRef90_Q4PLS0
UniRef50:
UniRef50_Q4PLS0
UniGene:
Mm.246598
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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