| Type | Description |
|---|---|
| Definition | transcription activation suppressor |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:28:00 | Periphilin self-association underpins epigenetic silencing by the HUSH complex. | 32976585 |
| 2020-10-24 14:12:00 | TASOR is a that directs HUSH complex assembly and epigenetic transposon control. | 33009411 |
| 2020-06-27 11:49:00 | Ablation of FAM208a in HEK293t cells did not impair the cell division processes. There is only a marginal effect of FAM208a depletion on cell proliferation as well as on the functionality of HUSH complex. | 31112734 |
| 2018-10-13 10:19:00 | Genes co-repressed by TRIM28 and FAM208A are evolutionarily young, or exhibit tissue-specific expression, are enriched in young L1s, and display evidence for regulation through LTR promoters. Finally, we demonstrate that the HUSH complex is also required to repress L1 elements in human cells. | 29728366 |
| 2017-01-14 11:56:00 | The haploid screen identified HUSH, an epigenetic heterochromatin repressor complex composed of three subunits, TASOR, MPP8 and Periphilin. (Review) | 26853531 |
| Type | IDs |
|---|---|
| Synonymous | C3orf63, FAM208A, RAP140, TASOR1, se89-1 |
| Gene |
UniProtKB-ID:
TASOR_HUMAN
UniprotKB:
Q9UK61
UniParc:
UPI0000422561,
UPI00019B21E9,
UPI00019B21E8,
UPI000013E320
EMBL:
AF273053,
AB029028,
BC129987,
AF180425,
AC099781,
AK094486
Ensembl:
ENSG00000163946
KO:
hsa:23272
|
| Nucleutide sequences |
EMBL-CDS:
AAI29988.1,
AAD55098.1,
BAA83057.1,
AAG34913.1
Ensembl_TRS:
ENST00000431842,
ENST00000355628,
ENST00000493960
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000399410,
ENSP00000347845,
ENSP00000417509
RefSeq:
NP_001352566.1,
NP_056039.2,
NP_001350869.1,
NP_001352565.1,
NP_001106207.1,
NP_001352564.1,
XP_006713141.1,
NP_001352567.1
|
| Others |
UniRef100:
UniRef100_Q9UK61
UniRef90:
UniRef90_Q9UK61
UniRef50:
UniRef50_Q9UK61
UniGene:
Hs.116877
CCDS:
CCDS2877.1,
CCDS46853.1,
CCDS87094.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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