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2326 FMO1

2326

FMO1

flavin containing monooxygenase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition flavin containing monooxygenase 1

研究结论

Date Results Publications
2020-04-18 10:29:00 Decreases in N'-oxidation activity (V (max)/K (m)) were observed for the FMO1(I303V), FMO3(N61S), FMO3(D132H), FMO3(V257M), and FMO3(E308G) variants in vitro when compared with their respective wild-type isoforms. 30381441
2019-05-04 12:42:00 Differential gene expression by SFRP2(+), FMO1(+), and COL11A1(+) fibroblasts suggests roles in matrix deposition, inflammatory cell retention, and connective tissue cell differentiation, respectively. 29080679
2018-01-27 11:21:00 Report developmental regulation of hepatic FMO1 expression. 26839369
2017-04-29 10:16:00 Study tested the genetic effects of three FMOs genes (FMO1, FMO3, and FMO6P) on nicotine dependence by performing targeted sequencing on 2,852 nicotine-dependent and nondependent smokers; identified significant association signals for gene FMO1 and FMO6P 28413702
2014-07-19 11:52:00 data support the role of FMO3 in the N-oxidation of OLA and implicate for the first time the contribution of FMO1 and its functional *6 variant in OLA disposition 23147717

名称对应

Type IDs
Gene
UniProtKB-ID: FMO1_HUMAN, A0A024R934_HUMAN, B2RCG5_HUMAN
UniprotKB: Q01740, A0A024R934, B2RCG5
UniParc: UPI000000DBBA, UPI0001914D1C, UPI00017508C1
EMBL: AY879266, AL445673, AK290113, M64082, CH471067, BC047129, AK315100, AL021026, AL031274, AK296198
Ensembl: ENSG00000010932
KO: hsa:2326
Nucleutide sequences
EMBL-CDS: EAW90892.1, AAA52457.1, AAH47129.1, BAH12280.1, BAF82802.1, AAW56076.1, EAW90894.1, EAW90895.1, BAG37562.1
Gene_ORFName: hCG_38488
Ensembl_TRS: ENST00000617670, ENST00000354841, ENST00000402921, ENST00000367750
Protein sequencees
Ensembl_PRO: ENSP00000385543, ENSP00000356724, ENSP00000346901, ENSP00000481732
RefSeq: NP_002012.1, XP_006711304.1, XP_005245094.1, NP_001269621.1, XP_006711305.1, NP_001269623.1, XP_005245095.1, NP_001269622.1
Others
UniRef100: UniRef100_B2RCG5, UniRef100_Q01740
UniRef90: UniRef90_Q01740
UniRef50: UniRef50_Q01740
UniGene: Hs.1424
CCDS: CCDS60351.1, CCDS1294.1

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