| Type | Description |
|---|---|
| Definition | OTU deubiquitinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:54:00 | Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells. | 32571254 |
| 2020-10-03 12:52:00 | MicroRNA 32 promotes cell proliferation, migration, and suppresses apoptosis in colon cancer cells by targeting OTU domain containing 3. | 31338872 |
| 2020-09-05 13:59:00 | Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity. | 32679077 |
| 2019-09-14 11:54:00 | Knockdown of OTUD3 results in a decrease in the level of GRP78 protein, suppression of cell growth and migration, and tumorigenesis in lung cancer. | 31266968 |
| 2016-04-30 11:14:00 | OTUD3 is an essential regulator of PTEN and the OTUD3-PTEN signalling axis plays a critical role in tumour suppression. | 26280536 |
| Type | IDs |
|---|---|
| Synonymous | DUBA4 |
| Gene |
UniProtKB-ID:
OTUD3_HUMAN
UniprotKB:
Q5T2D3
UniParc:
UPI000004DB04
EMBL:
AL391883,
AB007928
Ensembl:
ENSG00000169914
KO:
hsa:23252
|
| Nucleutide sequences |
EMBL-CDS:
BAA32304.2
Ensembl_TRS:
ENST00000375120
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000364261
RefSeq:
NP_056022.1,
XP_005245851.1,
XP_005245849.1,
XP_024310088.1,
XP_005245850.1
|
| Others |
UniRef100:
UniRef100_Q5T2D3
UniRef90:
UniRef90_Q5T2D3
UniRef50:
UniRef50_Q5T2D3
UniGene:
Hs.374987
CCDS:
CCDS41279.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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