| Type | Description |
|---|---|
| Definition | PH domain and leucine rich repeat protein phosphatase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:29:00 | PTEN and PHLPP crosstalk in cancer cells and in TGFbeta-activated stem cells. | 32294598 |
| 2021-02-06 13:55:00 | [Down-regulation of PHLPP1 expression ameliorates high glucose-induced autophagy inhibition and apoptosis promotion of podocytes by activating PI3K/AKT/mTOR pathway]. | 33441223 |
| 2020-12-12 13:27:00 | Distinct intra-mitochondrial localizations of pro-survival kinases and regulation of their functions by DUSP5 and PHLPP-1. | 32480039 |
| 2020-08-22 15:29:00 | Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice. | 31582730 |
| 2019-10-19 11:38:00 | PHLPP1 provides a proofreading step that maintains the fidelity of autoinhibition and reveals a prominent loss-of-function mechanism in cancer by suppressing the steady-state levels of | 30904392 |
| Type | IDs |
|---|---|
| Synonymous | PHLPP, PLEKHE1, PPM3A, SCOP |
| Gene |
UniProtKB-ID:
PHLP1_HUMAN
UniprotKB:
O60346
UniParc:
UPI00001C1FF8,
UPI000051AE2E
EMBL:
BC063519,
BC126277,
BC082244,
AB011178,
AC027553,
AC015989,
BC014927,
AK001924,
AC022046,
BC010706,
BC047653
Ensembl:
ENSG00000081913
KO:
hsa:23239
|
| Nucleutide sequences |
EMBL-CDS:
BAA91980.1,
AAH63519.1,
AAH14927.3,
BAA25532.2,
AAH10706.1,
AAI26278.1,
AAH82244.1,
AAH47653.1
Ensembl_TRS:
ENST00000262719
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262719
RefSeq:
XP_024306873.1,
NP_919431.2,
XP_011524188.1
|
| Others |
UniRef100:
UniRef100_O60346
UniRef90:
UniRef90_O60346
UniRef50:
UniRef50_Q9WTR8
UniGene:
Hs.465337
CCDS:
CCDS45881.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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