| Type | Description |
|---|---|
| Definition | ankyrin repeat domain 26 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-10 10:31:00 | the methylation of specific CpGs at the Ankrd26 promoter occurs in mice during HFD treatment and causes the down-regulation of Ankrd26 expression, at least in part, by impairing p300 binding to its promoter. We propose that the epigenetic silencing of the Ankrd26 gene contributes to VAT inflammation following unhealthy dieting. | 28266632 |
| 2016-01-16 11:31:00 | Deletion of the C-terminus of the protein encoded by Ankrd26 leads to changes in primary cilia in the brain, resulting in the disruption of the function of the melanocortin pathway and the HPA axis and leading to excessive food intake and obesity. | 24633808 |
| 2012-03-03 10:27:00 | Data indicate that Ankrd26 is involved in regulation of food intake and in regulation of insulin/insulin receptor signaling in white adipose tissue; partial inactivation of Ankrd26 leads to obesity and, thus, to diabetes type 2. | 21842266 |
| 2011-10-15 11:29:00 | conclude that Ankrd26 gene disruption promotes adipocyte differentiation at both the progenitor commitment and differentiation steps and that ERK activation plays a role in this process | 21669876 |
| 2010-01-21 00:00:00 | obesity and gigantism may be caused by a disruption of the Ankrd26 gene | 18162531 |
| Type | IDs |
|---|---|
| Synonymous | 5730521P14Rik, BC008111, mKIAA1074 |
| Gene |
UniProtKB-ID:
D3Z482_MOUSE
UniprotKB:
D3Z482
UniParc:
UPI00005120C9
EMBL:
AC036121,
AC140192
Ensembl:
ENSMUSG00000007827
KO:
mmu:232339
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000112830
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108449
RefSeq:
XP_036021957.1,
XP_006506086.1,
NP_001074581.1,
XP_006506087.1,
XP_006506088.1,
XP_030111214.1,
XP_006506085.1,
XP_036021958.1
|
| Others |
UniRef100:
UniRef100_D3Z482
UniRef90:
UniRef90_D3Z482
UniRef50:
UniRef50_M0R3T8
UniGene:
Mm.276116
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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