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232334 Vgll4

232334

Vgll4

vestigial like family member 4

protein-coding

Mus musculus

基因描述

Type Description
Definition vestigial like family member 4

研究结论

Date Results Publications
2019-12-28 11:49:00 Studies identified VGLL4 as a novel activator in regulating muscle regeneration at the differentiation stage, which provides new insights into the YAP-independent role of VGLL4 in skeletal muscle regeneration. 31328806
2019-06-01 10:04:00 VGLL4 acted as an adaptor protein that enhanced the interaction between TEAD4 and CtBP2, and this TEAD4-VGLL4-CtBP2 ternary complex dynamically existed at the early stage of adipogenesis. 30209132
2019-03-30 11:06:00 Results revealed an essential role of VGLL4 in heart valve morphogenesis via regulating valvar interstitial cells proliferation and apoptosis. Furthermore, its deletion resulted in progressive valve disease. These findings suggest that mutations in VGLL4 may underlie human congenital heart valve dysplasia. 30789911
2019-01-12 11:28:00 Adenovirus armed with VGLL4 selectively kills hepatocellular carcinoma in a mouse model with G2/M phase arrest and apoptosis promotion. 30119884
2017-06-24 12:12:00 VGLL4 inhibits cardiomyocyte proliferation by inhibiting TEAD1-YAP interaction and by targeting TEAD1 for degradation. 27720608

名称对应

Type IDs
Synonymous BC048841, VGL-4
Gene
UniProtKB-ID: VGLL4_MOUSE, Q3TQI9_MOUSE, Q3TSJ2_MOUSE
UniprotKB: Q80V24, Q3TQI9, Q3TSJ2
UniParc: UPI0000023476, UPI00001F414F, UPI00001C8DA9
EMBL: AK162019, AK163550, BC060305, BC048841
Ensembl: ENSMUSG00000030315
KO: mmu:232334
Nucleutide sequences
EMBL-CDS: AAH60305.1, AAH48841.1, BAE37393.1, BAE36683.1
Ensembl_TRS: ENSMUST00000032459
Protein sequencees
Ensembl_PRO: ENSMUSP00000032459
RefSeq: XP_006506076.1, NP_001343300.1, XP_006506077.1, XP_006506075.1, XP_036021953.1, NP_808351.1, XP_006506073.1
Others
UniRef100: UniRef100_Q3TQI9, UniRef100_Q80V24, UniRef100_Q3TSJ2
UniRef90: UniRef90_Q3TSJ2, UniRef90_A0A3L7H7H3, UniRef90_Q80V24
UniRef50: UniRef50_Q14135, UniRef50_Q80V24, UniRef50_Q14135-6
UniGene: Mm.268357, Mm.446323
CCDS: CCDS20436.1

全选

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研究热度

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