| Type | Description |
|---|---|
| Definition | histone deacetylase 11 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:14:00 | HDAC11 promotes meiotic apparatus assembly during mouse oocyte maturation via decreasing H4K16 and alpha-tubulin acetylation. | 31910069 |
| 2020-04-25 12:05:00 | study establishes HDAC11 as a unique type of target molecule that has therapeutic potential in myeloproliferative neoplasms | 31750881 |
| 2019-12-21 10:12:00 | Ex vivo and cell-based assays revealed that Hdac11 catalytic activity suppresses the BAT transcriptional program, in both the basal state and in response to beta-adrenergic receptor signaling, through a mechanism that is dependent on physical association with Brd2. These findings define an epigenetic pathway for the regulation of energy homeostasis. | 30089714 |
| 2019-07-20 13:30:00 | Loss of HDAC11 had no obvious impact on brain morphology and neural stem/precursor cells isolated from Hdac11 (KO/KO) mice had comparable proliferation and differentiation characteristics. However, in differentiating neural cells this study observed decreased expression of schizophrenia-associated gene Fez1. | 28928414 |
| 2019-03-30 12:23:00 | The translational significance of histone deacetylase 11 (HDAC11) targeting was shown by the ability of an HDAC11i to promote long-term allograft allografts. | 28819166 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HDA11_MOUSE,
Q543U1_MOUSE
UniprotKB:
Q91WA3,
Q543U1
UniParc:
UPI0000004079
EMBL:
AK045994,
BC016208
Ensembl:
ENSMUSG00000034245
KO:
mmu:232232
|
| Nucleutide sequences |
EMBL-CDS:
AAH16208.1,
BAC32565.1
Ensembl_TRS:
ENSMUST00000041736
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000043828
RefSeq:
NP_659168.1,
XP_036021947.1
|
| Others |
UniRef100:
UniRef100_Q91WA3
UniRef90:
UniRef90_Q91WA3
UniRef50:
UniRef50_Q91WA3
UniGene:
Mm.206218
CCDS:
CCDS20366.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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