Type | Description |
---|---|
Definition | deltex E3 ubiquitin ligase 4 |
Date | Results | Publications |
---|---|---|
2018-04-14 11:12:00 | Notch is ligand activated and undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 processing | 28611181 |
2012-05-05 10:04:00 | Our results provide molecular insight into the mechanisms by which NLRP4-DTX4 targets TBK1 for degradation. | 22388039 |
Type | IDs |
---|---|
Synonymous | RNF155 |
Gene |
UniProtKB-ID:
DTX4_HUMAN
UniprotKB:
Q9Y2E6
UniParc:
UPI00001C1F00,
UPI0000DBE49A
EMBL:
BC119011,
AB023154,
BC122861
Ensembl:
ENSG00000110042
KO:
hsa:23220
|
Nucleutide sequences |
EMBL-CDS:
BAA76781.1,
AAI22862.1,
AAI19012.1
Ensembl_TRS:
ENST00000532982,
ENST00000227451
|
Protein sequencees |
Ensembl_PRO:
ENSP00000434055,
ENSP00000227451
RefSeq:
NP_055992.1,
XP_006718546.1,
NP_001287656.1
|
Others |
UniRef100:
UniRef100_Q9Y2E6
UniRef90:
UniRef90_Q9Y2E6
UniRef50:
UniRef50_Q9Y2E6
UniGene:
Hs.523696
CCDS:
CCDS76408.1,
CCDS44612.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32937373 |
DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination. Sci Adv Syed Feroj Ahmed , Lori Buetow , Mads Gabrielsen , Sergio Lilla , Chatrin Chatrin , Gary J Sibbet , Sara Zanivan , Danny T Huang |
2020-08-01 | - |
30021884 |
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck |
2018-10-01 | - |
29507755 |
Cell Discov Yanan Yue , Jun Liu , Xiaolong Cui , Jie Cao , Guanzheng Luo , Zezhou Zhang , Tao Cheng , Minsong Gao , Xiao Shu , Honghui Ma , Fengqin Wang , Xinxia Wang , Bin Shen , Yizhen Wang , Xinhua Feng , Chuan He , Jianzhao Liu |
2018-01-01 | - |
28611181 |
Sci Signal Patricia Chastagner , Eric Rubinstein , Christel Brou |
2017-06-13 | - |
22939624 |
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell Mikko Taipale , Irina Krykbaeva , Martina Koeva , Can Kayatekin , Kenneth D Westover , Georgios I Karras , Susan Lindquist |
2012-08-31 |
NR1H3,
TRIM10,
SGK2,
PREB,
CDK3,
TNK2,
CDK4,
CDK6,
CDK7,
CDK9,
LOC400927-CSNK1E,
PCGF3,
TESK2,
MERTK,
KAT5,
CEBPE,
NPRL2,
CAMKK2,
MAP3K2,
FASTK,
RCBTB2,
PIM2,
WWP1,
CHEK1,
CDC37,
MAP4K1,
IRAK3,
TP53RK,
STK38,
KLHL32,
KLHL29,
FBXO17,
CLK2,
CLK3,
FBXO27,
ASB17,
RNF19B,
ACVR1C,
GRK7,
MAP3K8,
ASB6,
MYO3B,
RAB40A,
CSF1R,
FBXL14,
CSNK1A1,
CSNK1E,
HIPK4,
PDIK1L,
KLHL23,
SH3RF2,
SGK223,
DAPK3,
DCLK2,
ZBTB49,
DLX6,
DMPK,
EGFR,
EPHA2,
EPHA1,
EPHA4,
EPHB1,
EPHB6,
ERBB2,
ERBB3,
ERBB4,
AKT2,
ESR1,
PTK2B,
FBXL13,
FER,
FES,
MAPK15,
FGFR1,
FGFR3,
FGR,
ICK,
TRIM32,
TCF25,
STK38L,
FOXM1,
MAST2,
PASK,
LARP4B,
FBXO28,
DTX4,
FLT4,
ZC3H7B,
FBXW11,
TRIM2,
SF3B3,
TSSK2,
SGK3,
ALK,
FRK,
ABL1,
FYN,
KLHL34,
FBXL2
|
22388039 |
Nat. Immunol. Jun Cui , Yinyin Li , Liang Zhu , Dan Liu , Zhou Songyang , Helen Y Wang , Rong-Fu Wang |
2012-04-01 |
NLRP4,
DTX4,
TBK1,
IRF3
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
18976975 |
Genome-scale RNAi screen for host factors required for HIV replication. Cell Host Microbe Honglin Zhou , Min Xu , Qian Huang , Adam T Gates , Xiaohua D Zhang , John C Castle , Erica Stec , Marc Ferrer , Berta Strulovici , Daria J Hazuda , Amy S Espeseth |
2008-11-13 | - |
15684394 |
Normal immune system development in mice lacking the Deltex-1 RING finger domain. Mol. Cell. Biol. Sébastien Storck , Frédéric Delbos , Nicolas Stadler , Catherine Thirion-Delalande , Florence Bernex , Christophe Verthuy , Pierre Ferrier , Jean-Claude Weill , Claude-Agnès Reynaud |
2005-02-01 | - |
15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
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