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23219 FBXO28

23219

FBXO28

F-box protein 28

protein-coding

Homo sapiens

基因描述

Type Description
Definition F-box protein 28

研究结论

Date Results Publications
2020-12-12 13:24:00 SCF(FBXO28)-mediated self-ubiquitination of FBXO28 promotes its degradation. 31678254
2019-05-25 12:06:00 FBXO28 is a monogenic disease gene and contributes to the complex neurodevelopmental phenotype of the 1q41-q42 gene deletion syndrome. 30160831
2018-09-29 11:34:00 It was shown on human primary islets that FBXO28 improves pancreatic beta-cell survival under diabetogenic conditions without affecting insulin secretion. 29587369
2017-09-30 12:04:00 Expression levels of TP53BP2, FBXO28, and FAM53A genes were associated with patient survival specifically in ER-positive, TP53-mutated tumors. 28179588
2017-07-01 12:42:00 Fbxo28 regulates topoisomerase IIalpha decatenation activity and plays an important role in maintaining genomic stability. 27754753

名称对应

Type IDs
Synonymous CENP-30, Fbx28
Gene
UniProtKB-ID: FBX28_HUMAN
UniprotKB: Q9NVF7
UniParc: UPI0001824647, UPI000006F1C1
EMBL: BC031576, AB007952, AL390122, AK001628
Ensembl: ENSG00000143756
KO: hsa:23219
Nucleutide sequences
EMBL-CDS: BAA32327.1, BAA91795.1, AAH31576.1
Ensembl_TRS: ENST00000424254, ENST00000366862
Protein sequencees
Ensembl_PRO: ENSP00000416888, ENSP00000355827
RefSeq: NP_055991.1, NP_001129587.1
Others
UniRef100: UniRef100_Q9NVF7
UniRef90: UniRef90_Q9NVF7
UniRef50: UniRef50_Q9NVF7
UniGene: Hs.64691, Hs.713992
CCDS: CCDS44320.1, CCDS1539.1

全选

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研究热度

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