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23210 JMJD6

23210

JMJD6

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

protein-coding

Homo sapiens

基因描述

Type Description
Definition jumonji domain containing 6, arginine demethylase and lysine hydroxylase

研究结论

Date Results Publications
2021-03-06 13:24:00 JMJD6 Regulates Splicing of Its Own Gene Resulting in Alternatively Spliced Isoforms with Different Nuclear Targets. 32927736
2020-08-22 15:28:00 JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage. 32598339
2020-04-18 11:35:00 KRas-ERK signalling promotes the onset and maintenance of uveal melanoma through regulating JMJD6-mediated H2A.X phosphorylation 31736361
2020-04-04 11:50:00 Biophysical analyses, including crystallographic analyses of JMJD6(Delta344-403) in complex with iron and 2OG, supported its assignment as a lysyl hydroxylase rather than an N-methyl arginyl-demethylase. The screening results supported some, but not all, of the assigned JMJD6 substrates and identified other potential JMJD6 substrates 31147442
2020-03-07 11:35:00 Promotion of adipogenesis by JMJD6 requires the AT hook-like domain and is independent of its catalytic function 31430278

名称对应

Type IDs
Synonymous PSR, PTDSR, PTDSR1
Gene
UniProtKB-ID: JMJD6_HUMAN
UniprotKB: Q6NYC1
UniParc: UPI000020034E, UPI0000074746, UPI00003DFD0B
EMBL: AB011157, AK294816, AK021780, AC005837, BC047003, CH471099, AB073711, BC066654
Ensembl: ENSG00000070495
KO: hsa:23210
Nucleutide sequences
EMBL-CDS: BAG57932.1, BAC16755.1, BAG51050.1, AAH47003.1, AAH66654.1, BAA25511.1, EAW89434.1
Ensembl_TRS: ENST00000445478, ENST00000397625
Protein sequencees
Ensembl_PRO: ENSP00000380750, ENSP00000394085
RefSeq: NP_055982.2, NP_001074930.1
Others
UniRef100: UniRef100_Q6NYC1
UniRef90: UniRef90_Q6NYC1
UniRef50: UniRef50_Q6NYC1
UniGene: Hs.514505
CCDS: CCDS42383.1, CCDS42384.1

全选

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