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23208 SYT11

23208

SYT11

synaptotagmin 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition synaptotagmin 11

研究结论

Date Results Publications
2018-09-29 11:34:00 ATP13A2 and SYT11 form a functional network in the regulation of the autophagy-lysosome pathway, which may contribute to forms of Parkinson's Disease-associated neurodegeneration. 27278822
2018-09-22 11:36:00 parkin deficiency induces synaptotagmin-11 accumulation and PD-like neurotoxicity in mouse models, which is reversed by SYT11 knockdown in the SNpc or knockout of SYT11 restricted to dopaminergic neuron 29311685
2016-12-17 11:48:00 In summary, This study supports the existence of association between Parkinson disease and markers in or around SYT11 26944171
2014-09-20 10:47:00 The genetic variations of VAMP2, Synaptotagmin XI might be indication of the relationship between these genes and idiopathic generalized epilepsy 24164654
2010-01-21 00:00:00 Lack of disease-causing mutations in a detailed analysis of a large sample of familial and sporadic Parkinson's disease patients argues against a major role of mutations in the synaptotagmin XI gene in PD. 15354386

名称对应

Type IDs
Synonymous SYT12, sytXI
Gene
UniProtKB-ID: SYT11_HUMAN
UniprotKB: Q9BT88
UniParc: UPI00002049CC
EMBL: BC039205, AK027540, D38522, BC004291, CR749792, AK074931, BC013690, AL139128
Ensembl: ENSG00000132718
KO: hsa:23208
Nucleutide sequences
EMBL-CDS: AAH39205.1, AAH04291.1, AAH13690.1, CAH18653.1, BAB55186.1, BAC11300.1, BAA07527.2
Ensembl_TRS: ENST00000368324
Protein sequencees
Ensembl_PRO: ENSP00000357307
RefSeq: NP_689493.3, XP_005245071.1, XP_016856248.1
Others
UniRef100: UniRef100_Q9BT88
UniRef90: UniRef90_Q9BT88
UniRef50: UniRef50_Q9R0N3
UniGene: Hs.32984
CCDS: CCDS1122.1

全选

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