| Type | Description |
|---|---|
| Definition | ADP ribosylation factor like GTPase 6 interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 10:08:00 | Mutations in ARL6IP1, which encodes a tetraspan membrane protein localized to the endoplasmic reticulum (ER), have been recently described in a large family with a complicated form of hereditary spastic paraplegia (HSP). Phenotype associated with ARL6IP1 variants may be broader and more acute than so far reported and identifies fatal HSP as the severe end of the phenotypic spectrum of ARL6IP1 variants. | 31272422 |
| 2014-01-11 10:49:00 | ARL6ip1 is a three-spanning transmembrane protein with a conophylline binding pocket. | 24076029 |
| 2011-02-12 10:07:00 | Down-regulation of ARL6IP1 expression arrested CaSki cell cycling at the G0/G1 phase and mitigated CaSki cell migration, determined by wound healing assays. | 20213509 |
| 2010-07-19 12:05:00 | ARL6IP1 may play a key role in cisplatin-induced apoptosis in CaSki cervical cancer cells by regulating the expression of apoptosis-associated proteins. | 20372863 |
| 2010-01-21 00:00:00 | novel endoplasmic reticulum integral membrane protein which protects cells by inhibiting caspase-9 activity and reveal a possible role for ARMER in cell survival | 12754298 |
| Type | IDs |
|---|---|
| Synonymous | AIP1, ARL6IP, ARMER, SPG61 |
| Gene |
UniProtKB-ID:
AR6P1_HUMAN,
A0A024QYV7_HUMAN
UniprotKB:
Q15041,
A0A024QYV7
UniParc:
UPI00020650F1,
UPI000191507F,
UPI0000125D46
EMBL:
CH471186,
BC010281,
AC138811,
AK300869,
D31885,
AK301636
Ensembl:
ENSG00000170540
KO:
hsa:23204
|
| Nucleutide sequences |
EMBL-CDS:
BAH13361.1,
BAA06683.1,
AAH10281.1,
BAH13527.1,
EAW50258.1,
EAW50257.1
Gene_ORFName:
hCG_1994130
Ensembl_TRS:
ENST00000304414,
ENST00000546206
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000306788,
ENSP00000440048
RefSeq:
NP_055976.1,
NP_001300787.1
|
| Others |
UniRef100:
UniRef100_Q15041
UniRef90:
UniRef90_Q15041
UniRef50:
UniRef50_Q15041
UniGene:
Hs.634882
CCDS:
CCDS10572.1,
CCDS81951.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员