| Type | Description |
|---|---|
| Definition | Fas associated factor family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:21:00 | We present physiological evidence that UBXN3B positively regulates stimulator-of-interferon genes (STING) signaling. Mechanistic studies demonstrate that UBXN3B interacts with both STING and its E3 ligase TRIM56, and facilitates STING ubiquitination, dimerization, trafficking, and consequent recruitment and phosphorylation of TBK1. | 29899553 |
| 2017-11-11 13:50:00 | UBXD8 is necessary for sterol-stimulated dislocation of ubiquitylated HMGCR from the endoplasmic reticulum membrane en route to proteasomal degradation, a function dependent on its UBX domain. | 28882874 |
| 2017-06-10 12:31:00 | that newly synthesized UBXD8 is post-translationally inserted into discrete ER subdomains by a mechanism requiring cytosolic PEX19 and membrane-integrated PEX3, proteins hitherto exclusively implicated in peroxisome biogenesis | 27295553 |
| 2014-11-08 10:56:00 | role of UBXD8 in cellular responses to excess fatty acids | 24378746 |
| 2014-03-01 10:17:00 | the UAS domain of Ubxd8 mediates it's polymerization upon interaction with long-chain unsaturated fatty acids | 23720822 |
| Type | IDs |
|---|---|
| Synonymous | ETEA, UBXD8, UBXN3B |
| Gene |
UniProtKB-ID:
FAF2_HUMAN
UniprotKB:
Q96CS3
UniParc:
UPI000007478A
EMBL:
BC006145,
AB088120,
BC001069,
AB020694,
BC014001
Ensembl:
ENSG00000113194
KO:
hsa:23197
|
| Nucleutide sequences |
EMBL-CDS:
BAA74910.1,
AAH14001.2,
BAC22491.1,
AAH01069.2,
AAH06145.2
Ensembl_TRS:
ENST00000261942
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261942
RefSeq:
NP_055428.1,
XP_011532777.1
|
| Others |
UniRef100:
UniRef100_Q96CS3
UniRef90:
UniRef90_Q96CS3
UniRef50:
UniRef50_Q96CS3
UniGene:
Hs.484242
CCDS:
CCDS34296.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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