| Type | Description |
|---|---|
| Definition | F-box and leucine rich repeat protein 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:48:00 | Biallelic mutation of FBXL7 suggests a novel form of Hennekam syndrome. | 31633297 |
| 2020-10-31 13:20:00 | Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis. | 32839549 |
| 2015-09-12 10:21:00 | Fbxl18 regulates apoptosis by mediating ubiquitin-dependent proteasomal degradation of the pro-apoptotic protein Fbxl7 that may impact cellular processes involved in cell cycle progression. | 25654763 |
| 2015-08-08 11:39:00 | the Skp1.Cul1.F-box protein complex subunit Fbxl7 modulates mitochondrial function by controlling the cellular abundance of survivin | 25778398 |
| 2012-09-15 10:37:00 | FBXL7 specifically interacts with Aurora A during mitosis but not in interphase, suggesting a regulatory role for FBXL7 in controlling Aurora A abundance during mitosis. | 22306998 |
| Type | IDs |
|---|---|
| Synonymous | FBL6, FBL7 |
| Gene |
UniProtKB-ID:
FBXL7_HUMAN
UniprotKB:
Q9UJT9
UniParc:
UPI00005DC4AF,
UPI00000724E0
EMBL:
AB020647,
CH471102,
AC010638,
BC136424,
AC027332,
AF174593,
AF199356,
AC091970,
BC075061,
AC010477,
AC091872
Ensembl:
ENSG00000183580
KO:
hsa:23194
|
| Nucleutide sequences |
EMBL-CDS:
EAX08029.1,
AAH75061.1,
BAA74863.2,
AAF04514.1,
AAF09248.1,
AAI36425.1
Ensembl_TRS:
ENST00000504595,
ENST00000510662
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000425184,
ENSP00000423630
RefSeq:
NP_001265246.1,
XP_016864751.1,
XP_011512300.1,
NP_036436.1
|
| Others |
UniRef100:
UniRef100_Q9UJT9
UniRef90:
UniRef90_Q9UJT9
UniRef50:
UniRef50_Q9UJT9
UniGene:
Hs.433057
CCDS:
CCDS64129.1,
CCDS54833.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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