| Type | Description |
|---|---|
| Definition | autophagy related 4B cysteine peptidase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:29:00 | MiR-449a attenuates autophagy of T-cell lymphoma cells by downregulating ATG4B expression. | 32172731 |
| 2020-06-20 10:16:00 | Human HAP1 and HeLa cells lacking ATG4B exhibit a severe but incomplete defect in LC3/GABARAP processing and autophagy. By further genetic depletion of ATG4 isoforms using CRISPR-Cas9 and siRNA we uncover that ATG4A, ATG4C and ATGD all contribute to residual priming activity, which is sufficient to enable lipidation of endogenous GABARAPL1 on autophagic structures. | 30661429 |
| 2020-06-06 12:24:00 | the importance of the regulatory axis of SNHG16/miR-16/ATG4B underlying osteosarcoma progression and chemoresistance to cisplatin. | 31427084 |
| 2020-06-06 10:13:00 | Virus-encoded proteases play diverse roles in the efficient replication of enterovirus 71 (EV71), which is the causative agent of human hand, foot, and mouth disease (HFMD). ATG4B protein processes the viral polyprotein with its cysteine protease activity and helps EV71 replicate through a chemical biology strategy. | 31554687 |
| 2020-04-04 10:16:00 | miR-665-3p regulates autophagy by targeting ATG4B expression to relieve inflammation and apoptosis in intestinal ischemia/reperfusion. | 29706629 |
| Type | IDs |
|---|---|
| Synonymous | APG4B, AUTL1 |
| Gene |
UniProtKB-ID:
ATG4B_HUMAN,
B3KVU2_HUMAN
UniprotKB:
Q9Y4P1,
B3KVU2
UniParc:
UPI00015DF70D,
UPI00001C0AD4,
UPI0000411F07,
UPI000013FEA4,
UPI00001AF16F,
UPI00004E1932
EMBL:
AK027332,
AK125277,
AB023160,
AL080168,
AK027462,
AC133528,
AB066215,
AK123425,
AJ504652,
AK027763,
BC000719
Ensembl:
ENSG00000168397
KO:
hsa:23192
|
| Nucleutide sequences |
EMBL-CDS:
CAB45756.1,
BAB55353.1,
AAY14919.1,
CAD43219.1,
AAH00719.1,
BAC86110.1,
BAB55042.1,
BAB83890.1,
BAB55127.1,
BAA76787.2,
BAG53904.1
Ensembl_TRS:
ENST00000405546,
ENST00000402096,
ENST00000404914
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383964,
ENSP00000384661,
ENSP00000384259
RefSeq:
XP_005247050.2,
XP_005247053.1,
XP_024308533.1,
XP_016859129.1,
XP_016859127.1,
XP_005247052.1,
NP_037457.3,
XP_016859126.1,
XP_016859128.1,
XP_005247049.2,
NP_847896.1
|
| Others |
UniRef100:
UniRef100_B3KVU2,
UniRef100_Q9Y4P1
UniRef90:
UniRef90_B3KVU2,
UniRef90_Q9Y4P1
UniRef50:
UniRef50_Q9Y4P1,
UniRef50_B3KVU2
UniGene:
Hs.283610
CCDS:
CCDS46565.1,
CCDS46564.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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