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231805 Pilra

231805

Pilra

paired immunoglobin-like type 2 receptor alpha

protein-coding

Mus musculus

基因描述

Type Description
Definition paired immunoglobin-like type 2 receptor alpha

研究结论

Date Results Publications
2020-02-08 12:06:00 Upon neutrophil arrest, binding of PILR-beta1 to CD99 ceases, shifting the signaling balance towards inhibitory PILR-alpha. This enables integrin deactivation and supports cell diapedesis in venules of the mouse cremaster muscle. 31385804
2017-07-29 12:52:00 Data suggest that immune inhibitory receptor, PILRalpha, plays an important role in the prevention of obesity and liver fibrosis. 26840635
2017-05-20 14:34:00 Thus, Leda-1/Pianp is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10/17 and intramembrane protease gamma-secretase. 27349870
2016-02-20 11:29:00 negatively regulates inflammatory colitis by reducing the neutrophil and macrophage infiltration 25710489
2015-12-12 10:49:00 demonstrate that counter-regulation of the ligand-receptor pair Leda-1/Pianp and Pilralpha is part of the complex innate immune response of macrophages and its genetically determined strain-specific modulation 26188512

名称对应

Type IDs
Synonymous AV021745, FDF03
Gene
UniProtKB-ID: PILRA_MOUSE
UniprotKB: Q2YFS3
UniParc: UPI0000027745, UPI00000EA584
EMBL: AJ400844, AY823670, AK041413
Ensembl: ENSMUSG00000046245
KO: mmu:231805
Nucleutide sequences
EMBL-CDS: BAC30935.1, CAC01617.1, AAX39494.1
Ensembl_TRS: ENSMUST00000110980, ENSMUST00000058897
Protein sequencees
Ensembl_PRO: ENSMUSP00000106608, ENSMUSP00000050313
RefSeq: NP_705730.1
Others
UniRef100: UniRef100_Q2YFS3
UniRef90: UniRef90_Q2YFS3
UniRef50: UniRef50_Q2YFS3
UniGene: Mm.379385
CCDS: CCDS19780.1

全选

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研究热度

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