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23175 LPIN1

23175

LPIN1

lipin 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition lipin 1

研究结论

Date Results Publications
2021-03-13 13:15:00 Expression and clinicopathological significance of lipin-1 in human breast cancer and its association with p53 tumor suppressor gene. 31970786
2021-03-06 13:30:00 LPIN1 downregulation enhances anticancer activity of the novel HDAC/PI3K dual inhibitor FK-A11. 33274548
2021-02-13 13:29:00 MiRNA-584 suppresses the progression of ovarian cancer by negatively regulating LPIN1. 32096176
2020-12-19 13:45:00 Src links lipogenesis via lipin-1 to breast cancer malignancy. 33203880
2020-07-25 12:47:00 Study identified lipin1 to be involved in the production of a subset of cellular lipids, as a rate-limiting factor for HCV infection, and indicated that the enzymatic activity of lipin1 is required to build the membranous compartment dedicated to viral genome replication. Lipin1 is probably contributing to the formation of the viral replication machinery by locally providing certain lipids required. 31752156

名称对应

Type IDs
Synonymous PAP1
Gene
UniProtKB-ID: LPIN1_HUMAN
UniprotKB: Q14693
UniParc: UPI000012E864, UPI0000E5A246, UPI0002064F62, UPI0000E5A241, UPI00042DB65A, UPI0000EE2367, UPI0000141482
EMBL: AK290235, D80010, AK294853, CH471053, BC018071, AK293787, AC106875, AC012456, AK302922, AK294742, BC030537
Ensembl: ENSG00000134324
KO: hsa:23175
Nucleutide sequences
EMBL-CDS: BAG57885.1, BAH13844.1, EAX00918.1, BAG57957.1, EAX00920.1, BAF82924.1, AAH30537.1, BAG57200.1, BAA11505.1, AAY14695.1
Ensembl_TRS: ENST00000425416, ENST00000449576, ENST00000256720, ENST00000396097, ENST00000396098, ENST00000674199
Protein sequencees
Ensembl_PRO: ENSP00000379405, ENSP00000401522, ENSP00000256720, ENSP00000379404, ENSP00000397908, ENSP00000501331
RefSeq: XP_006711933.1, NP_001336133.1, NP_001336132.1, XP_016859118.1, NP_001336136.1, XP_016859113.1, XP_011508636.1, XP_011508638.1, XP_016859120.1, XP_006711935.1, XP_024308530.1, NP_001336134.1, XP_016859119.1, XP_024308531.1, XP_016859116.1, NP_001336129.1, NP_001248357.1, NP_001336137.1, NP_001248356.1, NP_663731.1, XP_011508637.1, XP_016859112.1, NP_001336135.1, NP_001336131.1, XP_016859117.1, XP_011508635.1, NP_001336130.1, XP_016859114.1, NP_001336128.1
Others
UniRef100: UniRef100_Q14693
UniRef90: UniRef90_Q14693
UniRef50: UniRef50_Q14693
UniGene: Hs.467740, Hs.739141
CCDS: CCDS58701.1, CCDS58699.1, CCDS1682.1

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